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Keywords: nucleosomal array
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Polyamine analogues: potent inducers of nucleosomal array oligomerization and inhibitors of yeast cell growth
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Journal:
Biochemical Journal
Biochem J (2007) 405 (3): 541–545.
Published: 13 July 2007
... of polyamine analogues has emerged as a viable strategy for therapeutic intervention. Previously, we showed that the naturally occurring polyamines spermidine and spermine were quite effective at inducing the oligomerization of nucleosomal arrays in vitro , suggesting that polyamines may play a key role...