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Keywords: nucleosome
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Biochem J (2024) 481 (4): 219–244.
Published: 14 February 2024
... nucleosome substrates, the study of multivalent chromatin interactions, and new technologies driving the next era of histone PTM research. Table 1. Chromatin reader domains grouped by histone PTM class Chromatin reader domains Methyl-lysine reader Example (PTM specificity): Function...
Articles
Biochem J (2014) 458 (1): 153–158.
Published: 20 January 2014
.... However, to perform these functions, they need to occupy their sites in chromatin. In the present study, we have systematically assessed TALE binding to chromatin substrates and find that in vitro TALEs bind to their target site on nucleosomes at the more accessible entry/exit sites...
Includes: Supplementary data
Articles
Biochem J (2012) 442 (3): 527–538.
Published: 24 February 2012
... respectively. EMSAs (electrophoretic mobility-shift assays) illustrated the ability of the Pdp1 PWWP domain to bind to the nucleosome core particle, and further mutagenesis experiments indicated the crucial role of this binding activity in histone H4K20 di- and tri-methylation in yeast cells. The present study...
Includes: Supplementary data
Articles
Biochem J (2011) 439 (3): 487–502.
Published: 13 October 2011
...Jin Zhao; Wee Leng Siew; Weiqi Sun; Norbert Lehming The nucleosomes occupying the chromosomal start sites of transcription contain the histone H2A variant H2A.Z in place of H2A. Upon galactose induction, nucleosomes are evicted from the GAL1 locus in Saccharomyces cerevisiae cells. H2A.Z (which...
Includes: Supplementary data
Articles
Articles
Biochem J (2008) 409 (3): 651–656.
Published: 15 January 2008
... topoisomerase I in the presence of camptothecin on a repeated trinucleotide sequence, (TTA) 35 , lying in chromosome XIII of Saccharomyces cerevisiae , we can conclude that nucleosomes represent a physical barrier for the enzyme activity. 1 To whom correspondence should be addressed (email...
Articles
Biochem J (2004) 377 (3): 641–651.
Published: 01 February 2004
...Wenzheng ZHANG; Yoshihide HAYASHIZAKI; Bruce C. KONE Recently, a new class of histone methyltransferases that plays an indirect role in chromatin silencing by targeting a conserved lysine residue in the nucleosome core was described, namely the Dot1 (disruptor of telomeric silencing) family [Feng...
Articles
Biochem J (2002) 368 (2): 611–620.
Published: 01 December 2002
... deposited in the Swiss-Prot database under accession number P83327. 25 6 2002 2 8 2002 6 8 2002 6 8 2002 The Biochemical Society, London ©2002 2002 anti-bacterial protein epithelium mucosal immunity nucleosome Abbreviations used: MALDI-TOF MS, matrix-assisted...