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Keywords: null mutations
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Caenorhabditis elegans triple null mutant lacking UDP-N-acetyl-D-glucosamine:α-3-D-mannoside β1,2-N-acetylglucosaminyltransferase I

Shaoxian ZHU, Andrew HANNEMAN, Vernon N. REINHOLD, Andrew M. SPENCE, Harry SCHACHTER
Journal: Biochemical Journal
Biochem J (2004) 382 (3): 995–1001.
https://doi.org/10.1042/BJ20040793
Published: 07 September 2004
... -acetylglucosaminyltransferase I (GnT I), an enzyme essential for hybrid, paucimannose and complex N -glycan synthesis. We now describe a worm with null mutations in all three GnT I genes, gly-14 (III);gly-12 gly-13 (X) ( III and X refer to the chromosome number). The triple-knock-out (TKO) worms have a normal phenotype...
View articletitled, Caenorhabditis elegans triple null mutant lacking UDP-N-acetyl-D-glucosamine:α-3-D-mannoside β1,2-N-acetylglucosaminyltransferase I
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