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Keywords: osteoporosis
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Articles

Down-regulated microRNA-199a-3p enhances osteogenic differentiation of bone marrow mesenchymal stem cells by targeting Kdm3a in ovariectomized rats

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Jian-Cheng Wu, Jie Sun, Jia-Cheng Xu, Zhen-Yu Zhou, Ya-Feng Zhang
Journal: Biochemical Journal
Biochem J (2021) 478 (4): 721–734.
https://doi.org/10.1042/BCJ20200314
Published: 18 February 2021
...Jian-Cheng Wu; Jie Sun; Jia-Cheng Xu; Zhen-Yu Zhou; Ya-Feng Zhang Osteoporosis is a prevalent systemic skeletal disorder entailing bone fragility and increased fracture risk, often emerging in post-menopausal life. Emerging evidence implicates the dysregulation of microRNAs (miRNAs or miRs...
View articletitled, Down-regulated microRNA-199a-3p enhances osteogenic differentiation of bone marrow mesenchymal stem cells by targeting Kdm3a in ovariectomized rats
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Includes: Supplementary data
Articles

Identification of substrate-specific inhibitors of cathepsin K through high-throughput screening

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Simon Law, Xin Du, Preety Panwar, Nicolette S. Honson, Tom Pfeifer, Michel Roberge, Dieter Brömme
Journal: Biochemical Journal
Biochem J (2019) 476 (3): 499–512.
https://doi.org/10.1042/BCJ20180851
Published: 05 February 2019
... collagens and has been implicated in various cardiovascular and musculoskeletal diseases, including osteoporosis [ 5 – 8 ]. * These authors contributed equally to this work. 6 11 2018 27 12 2018 7 1 2019 8 1 2019 Correspondence: Dieter Brömme ( dbromme...
View articletitled, Identification of substrate-specific inhibitors of cathepsin K through high-throughput screening
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Includes: Supplementary data
Articles

Gambogic acid inhibits osteoclast formation and ovariectomy-induced osteoporosis by suppressing the JNK, p38 and Akt signalling pathways

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Jianjun Ma, Yan Ma, Xuqiang Liu, Shuai Chen, Chao Liu, An Qin, Shunwu Fan
Journal: Biochemical Journal
Biochem J (2015) 469 (3): 399–408.
https://doi.org/10.1042/BJ20150151
Published: 23 July 2015
...Jianjun Ma; Yan Ma; Xuqiang Liu; Shuai Chen; Chao Liu; An Qin; Shunwu Fan Excessive osteoclast formation and bone resorption are key causes of osteoporosis. Natural compounds can serve as alternative therapeutic agents for the prevention and treatment of osteoporosis, and some natural compounds may...
View articletitled, Gambogic acid inhibits osteoclast formation and ovariectomy-induced osteoporosis by suppressing the JNK, p38 and Akt signalling pathways
Open the PDF for Gambogic acid inhibits osteoclast formation and ovariectomy-induced osteoporosis by suppressing the JNK, p38 and Akt signalling pathways in another window