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1-4 of 4
Keywords: p70 ribosomal S6 kinase (S6K)
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Articles
For a PDK1 inhibitor, the substrate matters
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2011) 433 (2): e1–e2.
Published: 22 December 2010
... 2011 kinase inhibitor phosphoinositide 3-kinase (PI3K) ribosomal S6 kinase (RSK) p70 ribosomal S6 kinase (S6K) serum- and glucocorticoid-induced protein kinase (SGK) Given the unique position of PDK1 upstream of many protein kinases, a selective PDK1 inhibitor would be a valuable research...
Articles
Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2011) 433 (2): 357–369.
Published: 22 December 2010
.../Akt1 cancer kinase inhibitor 3-phosphoinositide-dependent protein kinase (PDK1) phosphoinositide 3-kinase (PI3K) p90 ribosomal S6 kinase (RSK) p70 ribosomal S6 kinase (S6K) serum- and glucocorticoid-induced protein kinase (SGK) PDK1 (3-phosphoinositide-dependent protein kinase 1) plays...
Articles
Characterization of PF-4708671, a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)
Available to PurchaseLaura R. Pearce, Gordon R. Alton, Daniel T. Richter, John C. Kath, Laura Lingardo, Justin Chapman, Catherine Hwang, Dario R. Alessi
Journal:
Biochemical Journal
Biochem J (2010) 431 (2): 245–255.
Published: 28 September 2010
... (phosphoinositide-dependent kinase 1) via its PIF pocket and subsequently the T-loop (Thr 229 in S6K1) is phosphorylated [ 13 ]. Akt/protein kinase B (PKB) cancer kinase inhibitor phosphoinositide 3-kinase (PI3K) p70 ribosomal S6 kinase (S6K) serum- and glucocorticoid-induced protein kinase (SGK...
Includes: Supplementary data
Articles
Juan M. García-Martínez, Jennifer Moran, Rosemary G. Clarke, Alex Gray, Sabina C. Cosulich, Christine M. Chresta, Dario R. Alessi
Journal:
Biochemical Journal
Biochem J (2009) 421 (1): 29–42.
Published: 12 June 2009
... phosphoinositide 3-kinase (PI3K) p70 ribosomal S6 kinase (S6K) serum and glucocorticoid protein kinase (SGK) The mTOR (mammalian target of rapamycin) protein kinase lies at the nexus of signalling pathways that regulate cell growth and proliferation. Many cancer-driving mutations in genes...
