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Keywords: paxillin
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Articles
Biochem J (2014) 464 (1): 99–108.
Published: 23 October 2014
... physically associates with the LD1 motif of the focal adhesion protein paxillin. We reveal that MEKK2 induces paxillin ubiquitylation, and that this function requires both the paxillin LD1 motif and MEKK2 kinase activity. Finally, we demonstrate that MEKK2 promotes paxillin redistribution from focal...
Includes: Supplementary data
Articles
Biochem J (2009) 418 (1): 173–184.
Published: 28 January 2009
...Jing-Ming Dong; Lei-Shong Lau; Yuen-Wai Ng; Louis Lim; Ed Manser Paxillin, a major focal-adhesion complex component belongs to the subfamily of LIM domain proteins and participates in cell adhesion-mediated signal transduction. It is implicated in cell-motility responses upon activation of cell...
Includes: Supplementary data
Articles
Biochem J (2006) 393 (2): 565–573.
Published: 23 December 2005
... protein paxillin is required for the overall tyrosine phosphorylation of FAK in embryonic stem cells [Wade, Bohl and Vande Pol (2002) Oncogene 21 , 96–107]. In the present paper, we identify the minimal structural features of paxillin that are required to support overall FAK tyrosine phosphorylation...
Articles
Biochem J (2002) 365 (3): 591–603.
Published: 01 August 2002
... be addressed (e-mail [email protected] ). 10 1 2002 16 4 2002 3 5 2002 The Biochemical Society, London ©2002 2002 integrin motility phosphotyrosine paxillin Src Abbreviations used: CE, chicken embryo; CHO, Chinese-hamster ovary; ECM, extracellular matrix; EGFR...
Articles
Biochem J (2001) 356 (1): 233–240.
Published: 08 May 2001
... the cytoplasmic domain of the α1 integrin subunit are unable to form proper focal adhesions and that phosphorylation on tyrosine residues of focal adhesion components is reduced on α1β1-specific substrates. The α1 cytoplasmic sequence is a specific recognition site for focal adhesion components like paxillin...