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Keywords: peroxidases
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Articles
Biochem J (2021) 478 (9): 1795–1808.
Published: 14 May 2021
... the presence of hydrogen peroxide, indicated an additional H-bonding in the mutant protein, which is responsible for the peroxidase activity of the mutant Mb. We observed that in the presence of 5 mM H 2 O 2 , H64DOPA Mb oxidizes thioanisole and benzaldehyde with a 10 and 54 folds higher rate...
Includes: Supplementary data
Articles
Biochem J (2021) 478 (3): 669–684.
Published: 12 February 2021
... computational approaches to determine whether pathogenic variants share changes in structure and function, and to understand how these changes might occur. Three pathogenic variants (G41S, Y48H, A51V) cause an increase in apoptosome activation and peroxidase activity. Molecular dynamics simulations of these...
Includes: Supplementary data
Articles
Biochem J (2020) 477 (7): 1227–1240.
Published: 09 April 2020
... protects neuronal cells against apoptosis induced by exposure to hydrogen peroxide. Our study demonstrates that when human WT L-PGDS is in complex with heme, it exhibits a strong peroxidase activity thus behaving as a pseudo-peroxidase. Electron paramagnetic resonance studies confirm that heme in the L...
Includes: Supplementary data
Articles
Biochem J (2017) 474 (15): 2563–2572.
Published: 18 July 2017
... substrate protein that binds to the surface of MauG and is oxidized by the high-valent hemes via long-range electron transfer. Ascorbate was also shown to prolong the activity of a P107V MauG variant that is more prone to inactivation. A previously unknown ascorbate peroxidase activity of MauG was...