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Keywords: peroxisome
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Biochem J (2014) 461 (1): 125–135.
Published: 13 June 2014
...Kaija J. Autio; Werner Schmitz; Remya R. Nair; Eija M. Selkälä; Raija T. Sormunen; Ilkka J. Miinalainen; Peter J. Crick; Yuqin Wang; William J. Griffiths; Janardan K. Reddy; Myriam Baes; J. Kalervo Hiltunen Cholesterol is catabolized to bile acids by peroxisomal β-oxidation in which the side chain...
Includes: Supplementary data
Biochem J (2014) 460 (2): 273–282.
Published: 13 May 2014
...Ana Victoria C. Pilar; Rona Strasser; James McLean; Elizabeth Quinn; Normand Cyr; Hamed Hojjat; Anwer Hasil Kottarampatel; Armando Jardim LPEX7 ( Leishmania peroxin 7) is essential for targeting newly synthesized proteins with a PTS2 (peroxisome-targeting signal type 2) import signal into the...
Biochem J (2013) 451 (3): 345–352.
Published: 12 April 2013
...Frederica L. Theodoulou; Kristin Bernhardt; Nicole Linka; Alison Baker PMPs (peroxisome membrane proteins) play essential roles in organelle biogenesis and in co-ordinating peroxisomal metabolism with pathways in other subcellular compartments through transport of metabolites and the operation of...
Biochem J (2012) 447 (3): 353–361.
Published: 05 October 2012
... diphosphate synthase). NBPs inhibit also growth of amoebae of Dictyostelium discoideum in which their target is again FDPS. A fusion protein between FDPS and GFP (green fluorescent protein) was found, in D. discoideum , to localize to peroxisomes and to confer resistance to the NBP alendronate. GFP was also...
Biochem J (2012) 443 (1): 241–247.
Published: 14 March 2012
...Gennaro Agrimi; Annamaria Russo; Pasquale Scarcia; Ferdinando Palmieri The essential cofactors CoA, FAD and NAD + are synthesized outside the peroxisomes and therefore must be transported into the peroxisomal matrix where they are required for important processes. In the present study we have...
Biochem J (2011) 437 (3): 505–513.
Published: 13 July 2011
...Elizabeth Allen; Annick Moing; Jonathan A. D. Wattis; Tony Larson; Mickaël Maucourt; Ian A. Graham; Dominique Rolin; Mark A. Hooks ACN1 (acetate non-utilizing 1) is a short-chain acyl-CoA synthetase which recycles free acetate to acetyl-CoA in peroxisomes of Arabidopsis . Pulse-chase [2- 13 C...
Includes: Supplementary data
Biochem J (2011) 436 (3): 547–557.
Published: 27 May 2011
... mammalian ABCD proteins ALDP (adrenoleukodystrophy protein), ALDR (adrenoleukodystrophy-related protein) and PMP70 (70 kDa peroxisomal membrane protein) targeted faithfully to peroxisomes and P70R (PMP70-related protein) targeted to the ER (endoplasmic reticulum), as in the native host. The Arabidopsis...
Includes: Supplementary data
Biochem J (2011) 435 (3): 771–781.
Published: 13 April 2011
...Tatu J. K. Haataja; M. Kristian Koski; J. Kalervo Hiltunen; Tuomo Glumoff All of the peroxisomal β-oxidation pathways characterized thus far house at least one MFE (multifunctional enzyme) catalysing two out of four reactions of the spiral. MFE type 2 proteins from various species display great...
Includes: Supplementary data
Biochem J (2011) 434 (1): 161–170.
Published: 27 January 2011
... discovered a PtdIns3 P -synthesizing activity in peroxisomes of Saccharomyces cerevisiae and have demonstrated that the lipid kinase Vps34p is already associated with peroxisomes during biogenesis. However, although Vps34 is required, it is not essential for optimal peroxisome biogenesis. The function of...
Biochem J (2010) 432 (2): 227–236.
Published: 12 November 2010
... restored by transformation with both cefP and cefR (a regulatory gene located upstream of cefP ), but not with cefP alone. Fluorescence microscopy studies with an EGFP (enhanced green fluorescent protein)–SKL (Ser-Lys-Leu) protein (a peroxisomal-targeted marker) as a control showed that the red...
Includes: Supplementary data
Biochem J (2009) 423 (2): 145–155.
Published: 25 September 2009
... interaction with other organelles such as the Golgi apparatus, peroxisomes and plastids. In the present review we discuss the nature of the network, the role of shape-forming molecules such as the recently described reticulon family of proteins and the function of some of the major domains within the ER...
Includes: Multimedia, Supplementary data
Biochem J (2007) 401 (2): 365–375.
Published: 21 December 2006
...Wouter F. Visser; Carlo W. T. van Roermund; Lodewijk Ijlst; Hans R. Waterham; Ronald J. A. Wanders In recent years, much progress has been made with respect to the unravelling of the functions of peroxisomes in metabolism, and it is now well established that peroxisomes are indispensable organelles...
Biochem J (2006) 393 (2): 537–543.
Published: 23 December 2005
...Rob Ofman; Dave Speijer; René Leen; Ronald J. A. Wanders Proteomic analysis of mouse kidney peroxisomes resulted in the identification of a novel nudix hydrolase designated RP2p, which is encoded by the D7RP2e gene. RP2p consists of 357 amino acids and contains two conserved domains: a nudix...
Biochem J (2005) 389 (2): 397–401.
Published: 05 July 2005
...Takhar Kasumov; Jillian E. Adams; Fang Bian; France David; Katherine R. Thomas; Kathryn A. Jobbins; Paul E. Minkler; Charles L. Hoppel; Henri Brunengraber We reported previously that a substantial fraction of the acetyl groups used to synthesize malonyl-CoA in rat heart is derived from peroxisomal...
Biochem J (2004) 384 (1): 37–45.
Published: 09 November 2004
...Harald W. PLATTA; Wolfgang GIRZALSKY; Ralf ERDMANN Proteins harbouring a peroxisomal targeting signal of type 1 (PTS1) are recognized by the import receptor Pex5p in the cytosol which directs them to a docking and translocation complex at the peroxisomal membrane. We demonstrate the ubiquitination...
Biochem J (2004) 381 (3): 581–585.
Published: 27 July 2004
...Francesco M. LASORSA; Pasquale SCARCIA; Ralf ERDMANN; Ferdinando PALMIERI; Hanspeter ROTTENSTEINER; Luigi PALMIERI The yeast peroxisomal adenine nucleotide carrier, Ant1p, was shown to catalyse unidirectional transport in addition to exchange of substrates. In both transport modes, proton movement...
Biochem J (2004) 380 (2): 393–400.
Published: 01 June 2004
...Ventsislava Y. PETROVA; Diane DRESCHER; Anna V. KUJUMDZIEVA; Manfred J. SCHMITT Yeast catalase A (Cta1p) contains two peroxisomal targeting signals (SSN SKF ) localized at its C-terminus and within the N-terminal third of the protein, which both can target foreign proteins to peroxisomes. In the...
Biochem J (2002) 367 (2): 433–441.
Published: 15 October 2002
...Tiila-Riikka KIEMA; Jukka P. TASKINEN; Päivi L. PIRILÄ; Kari T. KOIVURANTA; Rik K. WIERENGA; J. Kalervo HILTUNEN Rat peroxisomal multifunctional enzyme type 1 (perMFE-1) is a monomeric protein of β-oxidation. We have defined five functional domains (A, B, C, D and E) in the perMFE-1 based on...
Biochem J (2002) 363 (3): 801–807.
Published: 24 April 2002
...Dean A. CUEBAS; Christopher PHILLIPS; Werner SCHMITZ; Ernst CONZELMANN; Dmitry K. NOVIKOV According to current views, the second peroxisomal β-oxidation pathway is responsible for the degradation of the side chain of bile acid intermediates. Peroxisomal multifunctional enzyme type 2 [peroxisomal...
Biochem J (2001) 353 (3): 673–680.
Published: 25 January 2001
...Steven HUYGHE; Minne CASTEELS; Anneleen JANSSEN; Liesbeth MEULDERS; Guy P. MANNAERTS; Peter E. DECLERCQ; Paul P. VAN VELDHOVEN; Myriam BAES The ontogeny of the following peroxisomal metabolic pathways was evaluated in mouse liver and brain: α-oxidation, β-oxidation and ether phospholipid synthesis...
Biochem J (2000) 346 (1): 177–184.
Published: 08 February 2000
...Rachel K. SZILARD; Richard A. RACHUBINSKI Peroxins are proteins required for peroxisome assembly and are encoded by the PEX genes. The Yarrowia lipolytica pex5-1 mutant fails to import a subset of peroxisomal matrix proteins, including those with a type 1 peroxisomal targeting signal (PTS1). Pex5p...