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Keywords: pharmacoperone
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Articles
Chemical validation and optimization of pharmacoperones targeting vasopressin type 2 receptor mutant
Jo Ann Janovick, Timothy P. Spicer, Thomas D. Bannister, Emery Smith, Vadivel Ganapathy, Louis Scampavia
Journal:
Biochemical Journal
Biochem J (2018) 475 (18): 2941–2953.
Published: 25 September 2018
...Jo Ann Janovick; Timothy P. Spicer; Thomas D. Bannister; Emery Smith; Vadivel Ganapathy; Louis Scampavia A series of compounds formerly identified by high-throughput screening was studied for their ability to serve as pharmacoperones for the vasopressin type 2 receptor (V2R) mutant L83Q, which...
