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Keywords: phosphatidic acid
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Biochem J (2008) 409 (1): 1–18.
Published: 11 December 2007
...Isabel Mérida; Antonia Ávila-Flores; Ernesto Merino DGKs (diacylglycerol kinases) are members of a unique and conserved family of intracellular lipid kinases that phosphorylate DAG (diacylglycerol), catalysing its conversion into PA (phosphatidic acid). This reaction leads to attenuation of DAG...
Includes: Multimedia, Supplementary data
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Biochem J (2006) 398 (1): 1–13.
Published: 27 July 2006
... phospholipase D, phosphatidic acid, PIPKs and PtdIns(4,5) P 2 , contributing to enhancement of PtdIns(4,5) P 2 -mediated cellular events and receptor signalling. Na + , Kir (inwardly rectifying K + ), Ca 2+ and TRP (transient receptor potential) ion channels are regulated by small G-proteins and membrane pools...
Includes: Multimedia, Supplementary data
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Biochem J (2006) 394 (2): 495–500.
Published: 10 February 2006
... interconversion of phosphatidic acid into DAG by LPP1. This may account for the effects of LPP1 on cell migration, as sustained DAG is known to down-regulate PKC isoforms in cells. Therefore the physiological changes in the expression levels of LPP1 might represent a heterologous desensitization mechanism...
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Biochem J (2002) 368 (3): 809–815.
Published: 15 December 2002
...Marc A. de la ROCHE; Janet L. SMITH; Maribel RICO; Silvia CARRASCO; Isabel MERIDA; Lucila LICATE; Graham P. CÔTÉ; Thomas T. EGELHOFF Diacylglycerol kinases (DGKs) phosphorylate the neutral lipid diacylglycerol (DG) to produce phosphatidic acid (PA). In mammalian systems DGKs are a complex family...
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Biochem J (2000) 345 (3): 401–415.
Published: 25 January 2000
...Mordechai LISCOVITCH; Malgorzata CZARNY; Giusy FIUCCI; Xiaoqing TANG Interaction of extracellular-signal molecules with cell-surface receptors often activates a phospholipase D (PLD)-mediated hydrolysis of phosphatidylcholine and other phospholipids, generating phosphatidic acid. The activation...