1-2 of 2
Keywords: phosphatidylinositol 5-phosphate 4-kinase (PI5P4K)
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles

The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site

Open Access
Jonathan H. Clarke, Maria-Luisa Giudici, John E. Burke, Roger L. Williams, David J. Maloney, Juan Marugan, Robin F. Irvine
Journal: Biochemical Journal
Biochem J (2015) 466 (2): 359–367.
https://doi.org/10.1042/BJ20141333
Published: 20 February 2015
... the intracellular functions of the enzyme. phosphatidylinositol 5-phosphate (PI5P) phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) Cells were grown to confluence, washed in cold PBS and lysed by scraping them off in boiling Laemmli sample...
View articletitled, The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site
Open the PDF for The function of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ) explored using a specific inhibitor that targets the PI5P-binding site in another window
Includes: Supplementary data
Articles

Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization

Open Access
Jonathan H. Clarke, Robin F. Irvine
Journal: Biochemical Journal
Biochem J (2013) 454 (1): 49–57.
https://doi.org/10.1042/BJ20130488
Published: 26 July 2013
... and reproduction in any medium, provided the original work is properly cited. dimerization lipid kinase activity phosphatidylinositol 5-phosphate (PtdIns5 P ) phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) PI5P4Ks (PtdIns5 P 4-kinases, EC 2.7.1.149) phosphorylate PtdIns5 P to PtdIns(4,5) P...
View articletitled, Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization
Open the PDF for Evolutionarily conserved structural changes in phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) isoforms are responsible for differences in enzyme activity and localization in another window
Includes: Supplementary data