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Keywords: phosphodiesterase 3AClose
Dong Keun Rhee, Jung Chae Lim, Steven C. Hockman, Faiyaz Ahmad, Dong Ho Woo, Youn Wook Chung, Shiwei Liu, Allison L. Hockman, Vincent C. Manganiello
Journal: Biochemical Journal
Biochem J (2016) 473 (22): 4205–4225.
Published: 10 November 2016
... phosphodiesterase 3A ( hPDE3A ) remain unknown. Here, we show that yeast expressing wild-type (WT) hPDE3A or K13R hPDE3A (putative ubiquitinylation site mutant) exhibited resistance or sensitivity to exogenous hydrogen peroxide (H 2 O 2 ), respectively. H 2 O 2 -stimulated ROS production was markedly increased...
Includes: Supplementary data