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Keywords: phospholipases
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Articles
Journal:
Biochemical Journal
Biochem J (2017) 474 (21): 3659–3673.
Published: 23 October 2017
..., testis-specific phospholipase C (PLC) isoform, known as PLC-zeta (PLCζ). Sperm PLCζ catalyses the hydrolysis of phosphatidylinositol 4,5-bisphosphate triggering cytosolic Ca 2+ oscillations through the inositol 1,4,5-trisphosphate signalling pathway. PLCζ is the smallest known mammalian PLC isoform...
Articles
Journal:
Biochemical Journal
Biochem J (2016) 473 (23): 4289–4310.
Published: 25 November 2016
...Shamshad Cockcroft; Padinjat Raghu Phospholipase C (PLC) is a receptor-regulated enzyme that hydrolyses phosphatidylinositol 4,5-bisphosphate (PI(4,5)P 2 ) at the plasma membrane (PM) triggering three biochemical consequences, the generation of soluble inositol 1,4,5-trisphosphate (IP 3 ), membrane...
Articles
Journal:
Biochemical Journal
Biochem J (2001) 354 (2): 369–378.
Published: 22 February 2001
...Ian G. GANLEY; Stephanie J. WALKER; Maria MANIFAVA; Donxia LI; H. Alex BROWN; Nicholas T. KTISTAKIS Phospholipase D (PLD)1 was phosphorylated in vivo and by an associated kinase in vitro following immunoprecipitation. Both phosphorylation events were greatly reduced in a catalytically inactive...
