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1-7 of 7
Keywords: phosphoproteomics
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Articles
Rayner M. L. Queiroz, Siân C. Piper, Johanna S. Rees, Sam Strickson, Emmanuel Briend, Choon Pei Low, G. John Ferguson, Kathryn S. Lilley, Antony P. Jackson, Donna K. Finch
Journal:
Biochemical Journal
Biochem J (2022) 479 (3): 225–243.
Published: 04 February 2022
... the signalling mechanism of this IL-7/T cell priming response we used total T cell populations in subsequent experiments. We undertook an untargeted evaluation of the total and phosphoproteomes after IL-7 stimulation. Correspondence: Johanna S. Rees ( [email protected] ) Homeostatic cytokines...
Includes: Supplementary data
Articles
Dominic P. Byrne, Christopher J. Clarke, Philip J. Brownridge, Anton Kalyuzhnyy, Simon Perkins, Amy Campbell, David Mason, Andrew R. Jones, Patrick A. Eyers, Claire E. Eyers
Journal:
Biochemical Journal
Biochem J (2020) 477 (13): 2451–2475.
Published: 02 July 2020
... for this article was enabled by the participation of University of Liverpool in an all-inclusive Read & Publish pilot with Portland Press and the Biochemical Society under a transformative agreement with JISC. inhibitor phosphoproteomics PLK4 protein kinase signalling substrate specificity...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2020) 477 (5): 853–871.
Published: 04 March 2020
... of the Biochemical Society 2020 CBL–CIPK LC–MS/MS phosphatases phosphoproteomics phosphosites The other known target of the CBL–CIPK module is ABR1 (phosphorylated by CIPK3) [ 91 ], WHY1 (phosphorylated by CIPK14) [ 92 ] and ACA8 (phosphorylated by CIPK9 and CIPK14) [ 93 ]. In vitro and in-gel...
Articles
Nazma Malik, Raja S. Nirujogi, Julien Peltier, Thomas Macartney, Melanie Wightman, Alan R. Prescott, Robert Gourlay, Matthias Trost, Dario R. Alessi, Athanasios Karapetsas
Journal:
Biochemical Journal
Biochem J (2019) 476 (20): 3081–3107.
Published: 30 October 2019
... inhibitors and recruited and activated at endosomes, through its phox homology domain binding to PtdIns(3)P. We undertook genetic and pharmacological phosphoproteomic screens to uncover novel SGK3 substrates. We identified 40 potential novel SGK3 substrates, including four endosomal proteins STX7 (Ser126...
Includes: Supplementary data
Articles
Darya Zibrova, Franck Vandermoere, Olga Göransson, Mark Peggie, Karina V. Mariño, Anne Knierim, Katrin Spengler, Cora Weigert, Benoit Viollet, Nicholas A. Morrice, Kei Sakamoto, Regine Heller
Journal:
Biochemical Journal
Biochem J (2017) 474 (6): 983–1001.
Published: 07 March 2017
... protection and angiogenesis, but the underlying mechanisms are incompletely understood. Using a label-free phosphoproteomic analysis, we identified glutamine:fructose-6-phosphate amidotransferase 1 (GFAT1) as an AMPK substrate. GFAT1 is the rate-limiting enzyme in the hexosamine biosynthesis pathway (HBP...
Includes: Supplementary data
Articles
Leo K. Iwai, Leo S. Payne, Maciej T. Luczynski, Francis Chang, Huifang Xu, Ryan W. Clinton, Angela Paul, Edward A. Esposito, Scott Gridley, Birgit Leitinger, Kristen M. Naegle, Paul H. Huang
Journal:
Biochemical Journal
Biochem J (2013) 454 (3): 501–513.
Published: 29 August 2013
... kinase data. Multiple clustering analysis of the phosphoproteomic data revealed several DDR2 candidate downstream signalling nodes, including SHP-2 (Src homology 2 domain-containing protein tyrosine phosphatase 2), NCK1 (non-catalytic region of tyrosine kinase adaptor protein 1), LYN, SHIP-2 [SH2 (Src...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2013) 450 (3): 619–628.
Published: 28 February 2013
... phosphoproteomics polyamine phosphoinositide 3-kinase (PI3K) PI3K (phosphoinositide 3-kinase) signalling is involved in the control of essential cellular functions downstream of RTKs (receptor tyrosine kinases), G-protein-coupled receptors and Ras [ 1 – 3 ]. Upon receptor stimulation, heterodimeric class...
Includes: Supplementary data