...Daochun Luo; Isabella Caniggia; Martin Post BOK (BCL-2-related ovarian killer) is a member of the pro-apoptotic BCL-2 family that is highly expressed in the human placenta. BOK excess causes increased trophoblast autophagy and apoptosis in pre-eclampsia, a pathological condition of hypoxia...

...′-GATCCACATCTGCTGGAAGG-3′ for β-actin. Detection of GCM1, FBW2 and RACK1 proteins in placenta was performed by immunohistochemistry as described previously [ 6 ]. In brief, formalin-fixed paraffin-embedded tissue sections of human term placenta were deparaffinized and subjected to immunostaining by incubation...

..., skin, placenta and lung tissue. SULT2B1b mRNA expression was detected in RNA isolated from term placenta, normal prostate, prostate carcinoma, benign prostate hyperplasia, LNCaP prostate cancer cells, breast cancer specimens and MCF-7 breast cancer cells. Immunohistochemical localization of SULT2B1b...

... in placenta. Sequence analysis predicts that the expressed proteins will be functional and consequently it was proposed that this family of proteases may have evolved to perform subspecialized functions of the closely related protease, cathepsin L, that is expressed in placental tissues of all mammalian...

...Oscar BRIZ; Maria A. SERRANO; Rocio I. R. MACIAS; Javier GONZALEZ-GALLEGO; Jose J. G. MARIN Recent functional studies have suggested that, in addition to simple diffusion, carrier-mediated transport may play an important role in foetal unconjugated bilirubin (UCB) uptake by the placenta. We have...

... of fetal anaemia. 1 To whom correspondence should be addressed (e-mail [email protected] ). 18 1 2001 14 3 2001 3 4 2001 The Biochemical Society, London ©2001 2001 caeruloplasmin divalent metal transporter 1 hephaestin IREG1 placenta transferrin receptor...

...Sachiko SUZUKI; Shigenobu TONÉ; Osamu TAKIKAWA; Toshikazu KUBO; Ichiro KOHNO; Yohsuke MINATOGAWA Indoleamine 2,3-dioxygenase (IDO)-initiated tryptophan degradation in the placenta has been implicated in the prevention of the allogeneic fetus rejection [Munn, Zhou, Attwood, Bondarev, Conway...

... to be consistent with variations in NF-1-binding sequences. These results indicate that PSF-B, but not PSF-A, is a member of the NF-1 family, which participates in the PSF complex and in the repression of the CS- A promoter in pituitary GC cells. Key words: chorionic somatomammotropins, NF-1, placenta, placental...

.... This 387kDa mosaic protein contained a signal peptide followed by a new association of eight different protein domains, including a pentraxin domain and a von Willebrand factor type A domain, ten EGF domains, and 34 complement control protein modules. The human polydom mRNA is strongly expressed in placenta...

...Gert ZIMMER; Frank OEFFNER; V. V MESSLING; Thomas TSCHERNIG; H GRÖNE; H KLENK; Georg HERRLER A mucin-type glycoprotein has been described in murine, rat and canine tissues as a differentiation antigen and influenza-virus receptor. We have cloned a cDNA from human placenta RNA encoding...