... and the ability to comprehensively identify and characterize dynamic interactions among stromal cells within the tissue microenvironment. Single cell RNA sequencing (scRNAseq) has emerged as a powerful tool for deconvolving cellular heterogeneity and holds promise for understanding the development and plasticity...

.... Affinities of these antibodies for the antigen vary. It is well accepted that the antibodies made in the primary response are multi-reactive and exhibit plasticity, whereas affinity-matured antibodies are rigid and monospecific. However, it has now been demonstrated that the affinity-matured monoclonal...

... white fat grows mainly after birth. However, both tissues have been shown to have great plasticity. Thus an apparent transformation of brown fat into white fat takes place during post-natal development. This observation raises questions about a possible conversion of brown into white adipocytes during...