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Keywords: platelet-derived growth factor (PDGF)
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Articles

Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130 Cas

Caroline Pellet-Many, Paul Frankel, Ian M. Evans, Birger Herzog, Manfred Jünemann-Ramírez, Ian C. Zachary
Journal: Biochemical Journal
Biochem J (2011) 435 (3): 609–618.
https://doi.org/10.1042/BJ20100580
Published: 13 April 2011
...-commercial use, distribution and reproduction in any medium, provided the original work is properly cited. chemotaxis glycosylation neuropilin-1 (NRP1) p130 Cas platelet-derived growth factor (PDGF) vascular endothelial growth factor (VEGF) siRNAs (small interfering RNAs) were purchased from...
View article titled, Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130 Cas
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Includes: Supplementary data
Articles

Role of cellular bioenergetics in smooth muscle cell proliferation induced by platelet-derived growth factor

Jessica Perez, Bradford G. Hill, Gloria A. Benavides, Brian P. Dranka, Victor M. Darley-Usmar
Journal: Biochemical Journal
Biochem J (2010) 428 (2): 255–267.
https://doi.org/10.1042/BJ20100090
Published: 13 May 2010
... be addressed (email [email protected] ). 13 1 2010 18 3 2010 24 3 2010 24 3 2010 © The Authors Journal compilation © 2010 Biochemical Society 2010 metabolic flux mitochondrion phosphoinositide 3-kinase (PI3K) platelet-derived growth factor (PDGF) proliferation vascular...
View article titled, Role of cellular bioenergetics in smooth muscle cell proliferation induced by platelet-derived growth factor
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Includes: Supplementary data
Articles

Inhibition of PDGF-BB by Factor VII-activating protease (FSAP) is neutralized by protease nexin-1, and the FSAP–inhibitor complexes are internalized via LRP

Lars Muhl, Anders Nykjaer, Malgorzata Wygrecka, Denis Monard, Klaus T. Preissner, Sandip M. Kanse
Journal: Biochemical Journal
Biochem J (2007) 404 (2): 191–196.
https://doi.org/10.1042/BJ20061630
Published: 14 May 2007
... 2007 atherosclerosis Factor VII-activating protease (FSAP) low-density lipoprotein receptor-related protein (LRP) platelet-derived growth factor (PDGF) protease nexin-1 (PN-1) serine protease inhibitor (Serpin) The FSAP (Factor VII-activating protease) is a serine protease containing...
View article titled, Inhibition of PDGF-BB by Factor VII-activating protease (FSAP) is neutralized by protease nexin-1, and the FSAP–inhibitor complexes are internalized via LRP
Open the PDF for Inhibition of PDGF-BB by Factor VII-activating protease (FSAP) is neutralized by protease nexin-1, and the FSAP–inhibitor complexes are internalized via LRP in another window
Includes: Supplementary data
Articles

Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB

Lingli Li, Trias Asteriou, Berit Bernert, Carl-Henrik Heldin, Paraskevi Heldin
Journal: Biochemical Journal
Biochem J (2007) 404 (2): 327–336.
https://doi.org/10.1042/BJ20061757
Published: 14 May 2007
... [email protected] ). 24 11 2006 21 2 2007 27 2 2007 27 2 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 dermal fibroblast growth factor hyaluronan synthase (HAS) hyaluronidase platelet-derived growth factor (PDGF) signal transduction...
View article titled, Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB
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Articles

Quantitative model of Ras–phosphoinositide 3-kinase signalling cross-talk based on co-operative molecular assembly

Harjeet Kaur, Chang Shin Park, Jodee M. Lewis, Jason M. Haugh
Journal: Biochemical Journal
Biochem J (2006) 393 (1): 235–243.
https://doi.org/10.1042/BJ20051022
Published: 12 December 2005
... Society, London 2006 mathematical modelling phosphoinositide 3-kinase (PI3K) platelet-derived growth factor (PDGF) Ras receptor tyrosine kinase signal transduction 1 These authors contributed equally to this work. 2 To whom correspondence should be addressed (email...
View article titled, Quantitative model of Ras–phosphoinositide 3-kinase signalling cross-talk based on co-operative molecular assembly
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Includes: Supplementary data
Articles

PKCδ mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: possible involvement of PKCδ in vascular hypertrophy

Chun Yuan Fan, Masato Katsuyama, Chihiro Yabe-Nishimura
Journal: Biochemical Journal
Biochem J (2005) 390 (3): 761–767.
https://doi.org/10.1042/BJ20050287
Published: 05 September 2005
... methionine as described previously [ 6 ]. activating transcription factor-1 (ATF-1) NADPH oxidase NOX1 platelet-derived growth factor (PDGF) prostaglandin F2α (PGF2α) protein kinase Cδ (PKCδ) Superoxide (O 2 − ) and hydrogen peroxide (H 2 O 2 ), the so-called reactive oxygen species, have...
View article titled, PKCδ mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: possible involvement of PKCδ in vascular hypertrophy
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Articles

Two conserved cysteine residues are critical for the enzymic function of the human platelet-derived growth factor receptor-β: evidence for different roles of Cys-822 and Cys-940 in the kinase activity

Joon-Won LEE, Jee-Eun KIM, Eun-Jung PARK, Jin-Hyun KIM, Chang-Hun LEE, Seung-Rock LEE, Jongbum KWON
Journal: Biochemical Journal
Biochem J (2004) 382 (2): 631–639.
https://doi.org/10.1042/BJ20040624
Published: 24 August 2004
... To whom correspondence should be addressed (email [email protected] ). 15 4 2004 3 6 2004 3 6 2004 The Biochemical Society, London 2004 catalysis cysteine kinase mutagenesis N -ethylmaleimide platelet-derived growth factor (PDGF) Platelet-derived growth factor...
View article titled, Two conserved cysteine residues are critical for the enzymic function of the human platelet-derived growth factor receptor-β: evidence for different roles of Cys-822 and Cys-940 in the kinase activity
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Articles

Ligand-induced recruitment of Na+/H+-exchanger regulatory factor to the PDGF (platelet-derived growth factor) receptor regulates actin cytoskeleton reorganization by PDGF

Jean-Baptiste DEMOULIN, Jeong Kon SEO, Simon EKMAN, Eva GRAPENGIESSER, Ulf HELLMAN, Lars RÖNNSTRAND, Carl-Henrik HELDIN
Journal: Biochemical Journal
Biochem J (2003) 376 (2): 505–510.
https://doi.org/10.1042/bj20030385
Published: 01 December 2003
... with the PDGF receptor tyro- sine kinase controls the extent of cytoskeleton reorganization in re- sponse to PDGF. Key words: chemotaxis, cytoskeleton, ezrin-binding protein 50 (EBP50), intracellular pH, Na+/H+ exchanger regulatory factor (NHERF), platelet-derived growth factor (PDGF). INTRODUCTION Platelet...
View article titled, Ligand-induced recruitment of Na+/H+-exchanger regulatory factor to the PDGF (platelet-derived growth factor) receptor regulates actin cytoskeleton reorganization by PDGF
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Articles

Differential regulation of extracellular signal-regulated protein kinases (ERKs) 1 and 2 by cAMP and dissociation of ERK inhibition from anti-mitogenic effects in rabbit vascular smooth muscle cells

Rosario COSPEDAL, Melvin LOBO, Ian ZACHARY
Journal: Biochemical Journal
Biochem J (1999) 342 (2): 407–414.
https://doi.org/10.1042/bj3420407
Published: 24 August 1999
... inhibited rabbit aortic VSMC mitogenesis induced by platelet-derived growth factor (PDGF)-BB by preventing the entry of cells into S-phase. cAMP-elevating agents partly inhibited the late phase (1-4 h) of activation of ERKs 1 and 2 induced by PDGF-BB without inhibiting the early phase of activity (5-15 min...
View article titled, Differential regulation of extracellular signal-regulated protein kinases (ERKs) 1 and 2 by cAMP and dissociation of ERK inhibition from anti-mitogenic effects in rabbit vascular smooth muscle cells
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