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1-9 of 9
Keywords: platelet-derived growth factor (PDGF)
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Articles
Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130 Cas
Open AccessCaroline Pellet-Many, Paul Frankel, Ian M. Evans, Birger Herzog, Manfred Jünemann-Ramírez, Ian C. Zachary
Journal:
Biochemical Journal
Biochem J (2011) 435 (3): 609–618.
Published: 13 April 2011
... use, distribution and reproduction in any medium, provided the original work is properly cited. chemotaxis glycosylation neuropilin-1 (NRP1) p130 Cas platelet-derived growth factor (PDGF) vascular endothelial growth factor (VEGF) NRP1 (neuropilin-1) is a transmembrane co-receptor...
Includes: Supplementary data
Articles
Role of cellular bioenergetics in smooth muscle cell proliferation induced by platelet-derived growth factor
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2010) 428 (2): 255–267.
Published: 13 May 2010
.... In addition, these studies suggest that the LDH pathway may play an important role in regulating the bioenergetic reserve of VSMCs and therefore may be integral to the hyperplastic VSMC phenotype. metabolic flux mitochondrion phosphoinositide 3-kinase (PI3K) platelet-derived growth factor (PDGF...
Includes: Supplementary data
Articles
Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2007) 404 (2): 327–336.
Published: 14 May 2007
...-derived growth factor (PDGF) signal transduction Human dermal fibroblasts (1×10 4 cells/well in 24-well plates) were cultured for 24 h in complete medium followed by 48 h in starvation medium. At this time, fresh starvation medium was added in the absence or presence of PDGF-BB (3–10 ng/ml...
Articles
Inhibition of PDGF-BB by Factor VII-activating protease (FSAP) is neutralized by protease nexin-1, and the FSAP–inhibitor complexes are internalized via LRP
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Journal:
Biochemical Journal
Biochem J (2007) 404 (2): 191–196.
Published: 14 May 2007
... receptor-related protein (LRP) platelet-derived growth factor (PDGF) protease nexin-1 (PN-1) serine protease inhibitor (Serpin) Wild-type and LRP −/− MEFs (mouse embryo fibroblasts) were cultivated in DMEM (Dulbecco's modified Eagle's medium; Invitrogen) with 10% (v/v) FCS (fetal calf serum...
Includes: Supplementary data
Articles
Quantitative model of Ras–phosphoinositide 3-kinase signalling cross-talk based on co-operative molecular assembly
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2006) 393 (1): 235–243.
Published: 12 December 2005
... Signaling Technology. Unless otherwise noted, all other reagents were from Sigma–Aldrich. 25 6 2005 12 8 2005 14 9 2005 14 9 2005 The Biochemical Society, London 2006 mathematical modelling phosphoinositide 3-kinase (PI3K) platelet-derived growth factor (PDGF) Ras...
Includes: Supplementary data
Articles
PKCδ mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: possible involvement of PKCδ in vascular hypertrophy
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2005) 390 (3): 761–767.
Published: 05 September 2005
... hypertrophy in the vascular cell lineage. 1 These authors made an equal contribution to this work. 2 To whom correspondence should be addressed (email [email protected] ). activating transcription factor-1 (ATF-1) NADPH oxidase NOX1 platelet-derived growth factor (PDGF...
Articles
Journal:
Biochemical Journal
Biochem J (2004) 382 (2): 631–639.
Published: 24 August 2004
... catalysis cysteine kinase mutagenesis N -ethylmaleimide platelet-derived growth factor (PDGF) Platelet-derived growth factor receptor-β (PDGFR-β) belongs to a family of RTKs (receptor tyrosine kinases) and triggers the propagation of cellular signals by activating their intrinsic tyrosine...
Articles
Ligand-induced recruitment of Na+/H+-exchanger regulatory factor to the PDGF (platelet-derived growth factor) receptor regulates actin cytoskeleton reorganization by PDGF
Available to PurchaseJean-Baptiste DEMOULIN, Jeong Kon SEO, Simon EKMAN, Eva GRAPENGIESSER, Ulf HELLMAN, Lars RÖNNSTRAND, Carl-Henrik HELDIN
Journal:
Biochemical Journal
Biochem J (2003) 376 (2): 505–510.
Published: 01 December 2003
... with the PDGF receptor tyro- sine kinase controls the extent of cytoskeleton reorganization in re- sponse to PDGF. Key words: chemotaxis, cytoskeleton, ezrin-binding protein 50 (EBP50), intracellular pH, Na+/H+ exchanger regulatory factor (NHERF), platelet-derived growth factor (PDGF). INTRODUCTION Platelet...
Articles
Differential regulation of extracellular signal-regulated protein kinases (ERKs) 1 and 2 by cAMP and dissociation of ERK inhibition from anti-mitogenic effects in rabbit vascular smooth muscle cells
Available to Purchase
Journal:
Biochemical Journal
Biochem J (1999) 342 (2): 407–414.
Published: 24 August 1999
... inhibited rabbit aortic VSMC mitogenesis induced by platelet-derived growth factor (PDGF)-BB by preventing the entry of cells into S-phase. cAMP-elevating agents partly inhibited the late phase (1-4 h) of activation of ERKs 1 and 2 induced by PDGF-BB without inhibiting the early phase of activity (5-15 min...
