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Keywords: poly(ADP-ribose) polymerase 1 (PARP1)
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Biochem J (2015) 469 (2): 189–198.
Published: 06 July 2015
..., this molecule may also be involved in many other cellular and biological outcomes such as chromatin remodelling, gene transcription, genomic integrity, cell division, calcium signalling, circadian clock and pluripotency. Poly(ADP-ribose) polymerase 1 (PARP1) is such an enzyme and dysfunctional PARP1...
Includes: Supplementary data
Biochem J (2013) 449 (3): 623–630.
Published: 09 January 2013
...) poly(ADP-ribose) polymerase 1 (Parp1) poly(ADP-ribosyl)ation (PARylation) Parp1 also orchestrates genome organization by regulating genome-wide transcription [ 7 ] and epigenetic states of chromatin [ 8 ]. In the latter, Parp1 leads to chromatin decondensation, PARylating itself as well as...
Includes: Supplementary data
Biochem J (2012) 441 (2): 645–652.
Published: 21 December 2011
... properly cited. CCCTC-binding factor (Ctcf) DNA methylation DNA methyltranferase 1 (Dnmt1) epigenetics poly(ADPribosyl)ation (PARylation) poly(ADP-ribose) polymerase 1 (Parp1) PARylation [poly(ADP-ribosyl)ation] is a post-synthetic modification catalysed by a family of enzymes known as...
Includes: Supplementary data