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Keywords: polyglutamine tract
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Articles
Biochem J (2008) 412 (2): 191–209.
Published: 14 May 2008
... trinucleotide repeat expansion encoding an abnormally long polyglutamine tract in the huntingtin protein. Much has been learnt since the mutation was identified in 1993. We review the functions of wild-type huntingtin. Mutant huntingtin may cause toxicity via a range of different mechanisms. The primary...
Articles
Biochem J (2004) 378 (1): 229–238.
Published: 15 February 2004
...Miriam LLORIAN; Monique BEULLENS; Isabel ANDRÉS; Jose-Miguel ORTIZ; Mathieu BOLLEN We have identified a polypeptide that was already known to interact with polyglutamine-tract-binding protein (PQBP)-1/Npw38 as a novel splicing factor and interactor of protein phosphatase-1, hence the name SIPP1 for...