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Keywords: polysaccharide
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Articles

Molecular basis for recognition of the Group A Carbohydrate backbone by the PlyC streptococcal bacteriophage endolysin

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Harley King, Sowmya Ajay Castro, Amol Arunrao Pohane, Cynthia M. Scholte, Vincent A. Fischetti, Natalia Korotkova, Daniel C. Nelson, Helge C. Dorfmueller
Journal: Biochemical Journal
Biochem J (2021) 478 (12): 2385–2397.
https://doi.org/10.1042/BCJ20210158
Published: 25 June 2021
... the nature of the CBDs and only a few binding epitopes for CBDs have been elucidated. The major cell wall components of many streptococci are the polysaccharides that contain the polyrhamnose (pRha) backbone modified with species-specific and serotype-specific glycosyl side chains. In this report, using...
View articletitled, Molecular basis for recognition of the Group A Carbohydrate backbone by the PlyC streptococcal bacteriophage endolysin
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Includes: Supplementary data
Articles

Macromolecular assemblies of complex polysaccharides with galectin-3 and their synergistic effects on function

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Tao Zhang, Michelle C. Miller, Yi Zheng, Zhongyu Zhang, Huiting Xue, Dongyang Zhao, Jiyong Su, Kevin H. Mayo, Yifa Zhou, Guihua Tai
Journal: Biochemical Journal
Biochem J (2017) 474 (22): 3849–3868.
https://doi.org/10.1042/BCJ20170143
Published: 09 November 2017
...Tao Zhang; Michelle C. Miller; Yi Zheng; Zhongyu Zhang; Huiting Xue; Dongyang Zhao; Jiyong Su; Kevin H. Mayo; Yifa Zhou; Guihua Tai Although pectin-derived polysaccharides can antagonize galectin function in various pathological disorders, the nature of their binding interactions needs to be better...
View articletitled, Macromolecular assemblies of complex polysaccharides with galectin-3 and their synergistic effects on function
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Includes: Supplementary data
Articles

Giant mimivirus R707 encodes a glycogenin paralogue polymerizing glucose through α- and β-glycosidic linkages

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Anna J. Rommel, Andreas J. Hülsmeier, Simon Jurt, Thierry Hennet
Journal: Biochemical Journal
Biochem J (2016) 473 (20): 3451–3462.
https://doi.org/10.1042/BCJ20160280
Published: 11 October 2016
.... Mimivirus-encoded glycans play a role in the infection of host amoebae. Co-infection of Acanthamoeba with mimivirus and amylose and chitin hydrolysate reduced the number of infected amoebae, thus supporting the importance of polysaccharide chains in the uptake of mimivirus by amoebae. The identification...
View articletitled, Giant mimivirus R707 encodes a glycogenin paralogue polymerizing glucose through α- and β-glycosidic linkages
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Includes: Supplementary data
Articles

Fingerprinting of hydroxyl radical-attacked polysaccharides by N -isopropyl-2-aminoacridone labelling

Open Access
Robert A. M. Vreeburg, Othman B. Airianah, Stephen C. Fry
Journal: Biochemical Journal
Biochem J (2014) 463 (2): 225–237.
https://doi.org/10.1042/BJ20140678
Published: 22 September 2014
...Robert A. M. Vreeburg; Othman B. Airianah; Stephen C. Fry Hydroxyl radicals ( • OH) cause non-enzymic scission of polysaccharides in diverse biological systems. Such reactions can be detrimental (e.g. causing rheumatic and arthritic diseases in mammals) or beneficial (e.g. promoting the softening...
View articletitled, Fingerprinting of hydroxyl radical-attacked polysaccharides by N -isopropyl-2-aminoacridone labelling
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Includes: Supplementary data
Articles

Macromolecular and small-molecule modulation of intracellular Aβ 42 aggregation and associated toxicity

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Sohini Chakrabortee, Yun Liu, Liao Zhang, Helena R. Matthews, Hanrui Zhang, Ni Pan, Chun-ru Cheng, Shu-hong Guan, De-an Guo, Zebo Huang, Yizhi Zheng, Alan Tunnacliffe
Journal: Biochemical Journal
Biochem J (2012) 442 (3): 507–515.
https://doi.org/10.1042/BJ20111661
Published: 24 February 2012
.... Thus a molecular shield protein AavLEA1 [ Aphelenchus avenae LEA (late embryogenesis abundant) protein 1], which limits aggregation of proteins with expanded poly(Q) repeats, is also effective against Aβ 42 –EGFP when co-expressed in T-REx293 cells. A screen of polysaccharide and small organic...
View articletitled, Macromolecular and small-molecule modulation of intracellular Aβ 42 aggregation and associated toxicity
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Includes: Supplementary data
Articles

Inhibition of polyglutamine-mediated proteotoxicity by Astragalus membranaceus polysaccharide through the DAF-16/FOXO transcription factor in Caenorhabditis elegans

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Hanrui Zhang, Ni Pan, Siqin Xiong, Shenglong Zou, Haifeng Li, Lingyun Xiao, Zhijian Cao, Alan Tunnacliffe, Zebo Huang
Journal: Biochemical Journal
Biochem J (2012) 441 (1): 417–424.
https://doi.org/10.1042/BJ20110621
Published: 14 December 2011
... polyQ (polyglutamine) aggregation in Huntington's disease. Astragalus membranaceus polysaccharide (astragalan) has recently been shown to modulate aging and proteotoxic stress pathways. Using Caenorhabditis elegans models, we now show that astragalan not only reduces polyQ aggregation, but also...
View articletitled, Inhibition of polyglutamine-mediated proteotoxicity by Astragalus membranaceus polysaccharide through the DAF-16/FOXO transcription factor in Caenorhabditis elegans
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Includes: Supplementary data
Articles

The unique features of glycolytic pathways in Archaea

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Corné H. VERHEES, Servé W. M. KENGEN, Judith E. TUININGA, Gerrit J. SCHUT, Michael W. W. ADAMS, Willem M. de VOS, John van der OOST
Journal: Biochemical Journal
Biochem J (2003) 375 (2): 231–246.
https://doi.org/10.1042/bj20021472
Published: 15 October 2003
[email protected] ). 20 9 2002 16 5 2003 18 8 2003 18 8 2003 The Biochemical Society, London ©2003 2003 Archaea Embden—Meyerhof pathway Entner—Douderoff pathway glycolysis glycolytic enzyme polysaccharide Abbreviations used: AOR, aldehyde oxidoreductase; ED, Entner...
View articletitled, The unique features of glycolytic pathways in Archaea
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Articles

New type of starch-binding domain: the direct repeat motif in the C-terminal region of Bacillus sp. no. 195 α-amylase contributes to starch binding and raw starch degrading

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Jun-ichi SUMITANI, Tadashi TOTTORI, Takashi KAWAGUCHI, Motoo ARAI
Journal: Biochemical Journal
Biochem J (2000) 350 (2): 477–484.
https://doi.org/10.1042/bj3500477
Published: 23 August 2000
... will appear in DDBJ, EMBL and GenBank Nucleotide Sequence Databases under the accession number AB006823. 26 1 2000 19 5 2000 21 6 2000 The Biochemical Society, London © 2000 2000 glucoamylase polysaccharide post-translational processing Biochem. J. (2000) 350, 477 484...
View articletitled, New type of starch-binding domain: the direct repeat motif in the C-terminal region of Bacillus sp. no. 195 α-amylase contributes to starch binding and raw starch degrading
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