...Kusum Lata; Gregor Anderluh; Kausik Chattopadhyay Cholesterol-dependent cytolysins (CDCs) are the distinct class of β-barrel pore-forming toxins (β-PFTs) that attack eukaryotic cell membranes, and form large, oligomeric, transmembrane β-barrel pores. Listeriolysin O (LLO) is a prominent member...

...Reema Kathuria; Anish Kumar Mondal; Rohan Sharma; Samarjit Bhattacharyya; Kausik Chattopadhyay Vibrio cholerae cytolysin (VCC) is a β-barrel pore-forming toxin with potent membrane-damaging cell-killing activity. Previous studies employing the model membranes of lipid vesicles (liposomes) have...

... other human cell active toxins from Bt Cry41Aa did not induce apoptosis, but that its mechanism of action was consistent with that of a pore-forming toxin. The toxin induced a rapid and significant decrease in metabolic activity. Adenosine triphosphate depletion, cell swelling and membrane damage were...

...Isabel Gómez; Jorge Sánchez; Carlos Muñoz-Garay; Violeta Matus; Sarjeet S. Gill; Mario Soberón; Alejandra Bravo Cry proteins from Bacillus thuringiensis are insecticidal PFTs (pore-forming toxins). In the present study, we show that two distinct functional pre-pores of Cry1Ab are formed after...

... thuringiensis cadherin Cry toxin pore-forming toxin receptor binding Bacillus thuringiensis pore-forming toxins are valuable tools for the control of insect pests in agriculture and also against mosquitoes that are vectors of human diseases [ 1 ]. For the control of mosquitoes, B. thuringiensis...

... (parasitophorous vacuole) that separates the host cell cytoplasm from the parasite surface. The pore-forming toxin, SLO (streptolysin O), binds to cholesterol-containing membranes and can be used to selectively permeabilize the host cell membrane while leaving the PV membrane intact. We found that in mixtures...

...Olivier Joubert; Gabriella Viero; Daniel Keller; Eric Martinez; Didier A. Colin; Henri Monteil; Lionel Mourey; Mauro Dalla serra; Gilles Prévost The staphylococcal α-toxin and bipartite leucotoxins belong to a single family of pore-forming toxins that are rich in β-strands, although...

... d'Odontologie, Société Parogène, 11 rue Humann, 67085 Strasbourg Cedex, France. fluorescence resonance energy transfer (FRET) leucotoxin oligomerization pore-forming toxin protein–protein interaction Staphylococcus aureus Staphylococcus aureus is a major human pathogen, frequently...

... membrane interaction. 1 To whom correspondence should be addressed (email [email protected] ). 13 4 2004 2 7 2004 19 8 2004 19 8 2004 The Biochemical Society, London 2004 actinoporin amphipathic helix membrane interaction pore-forming toxin Pore...