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Keywords: precursor protein processing
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Articles
Endocytic delivery of intramolecularly quenched substrates and inhibitors to the intracellular yeast Kex2 protease1
Available to PurchaseM. Kerstin HENKEL, Gregory POTT, Andreas W. HENKEL, Luiz JULIANO, Chih-Min KAM, James C. POWERS, Alex FRANZUSOFF
Journal:
Biochemical Journal
Biochem J (1999) 341 (2): 445–452.
Published: 08 July 1999
... yeast revealed fluorescence due to specific cleavage by Kex2 protease in endosomal compartments. Furthermore, the endocytic delivery of protease inhibitors interfered with Kex2 activity for precursor protein processing. These observations reveal that the endocytic pathway does intersect with the cycling...
