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Keywords: premature senescence
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Articles
Role of p38 MAPK pathway in BMP4-mediated Smad-dependent premature senescence in lung cancer cells
Available to PurchaseDongmei Su, Xiue Peng, Shan Zhu, Ying Huang, Zhixiong Dong, Yu Zhang, Jianchao Zhang, Qian Liang, Jun Lu, Baiqu Huang
Journal:
Biochemical Journal
Biochem J (2011) 433 (2): 333–343.
Published: 22 December 2010
... appears to be due to multiple pathways activated by BMP4 itself. Our previous studies have demonstrated that BMP4 is able to drive lung cancer cells into a process of premature senescence; however, the signalling pathways, as well their interplays and roles associated with this process, are not well...
Includes: Supplementary data