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Yinghong Gao, Stephen P. Davies, Martin Augustin, Anna Woodward, Umesh A. Patel, Robert Kovelman, Kevin J. Harvey
Journal:
Biochemical Journal
Biochem J (2013) 451 (2): 313–328.
Published: 28 March 2013
... activity profiles illustrates how they relate to chemical structure similarities and provides new insights into inhibitor specificity and potential applications for probing new targets. Using this broad dataset, we provide a framework for assessing polypharmacology. We not only discover likely off-target...
Includes: Supplementary data
