Skip Nav Destination
Close Modal
Update search
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
Filter
- Title
- Author
- Author Affiliations
- Full Text
- Abstract
- Keyword
- DOI
- ISSN
- EISSN
- Issue
- Volume
- References
NARROW
Format
Subjects
Article Type
Date
Availability
1-27 of 27
Keywords: proliferation
Close
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Sort by
Articles
PON2 mediates mitochondrial dysfunction in tracheal epithelial cells in response to a quorum sensing molecule N-(-3-oxododecanoyl)-l-homoserine lactone
Available to PurchaseAaron G. Whitt, Shuhan Meng, Jiu-Zhen Jin, Lindsey R. Conroy, Lindsey A. McNally, Joseph A. Burlison, Bradford G. Hill, Brian F. Clem, Carl White, Chi Li
Journal:
Biochemical Journal
Biochem J (2022) 479 (19): 2013–2034.
Published: 07 October 2022
... PON2 modulates the effects of C12 at subtoxic concentrations using immortalized murine tracheal epithelial cells (TECs) isolated from wild-type (WT) or PON2-knockout (PON2-KO) mice. Our data reveal that C12 at subtoxic concentrations disrupts mitochondrial bioenergetics to hinder cellular proliferation...
Includes: Supplementary data
Articles
GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling
Open AccessClare Stretton, Thorsten M. Hoffmann, Michael J. Munson, Alan Prescott, Peter M. Taylor, Ian G. Ganley, Harinder S. Hundal
Journal:
Biochemical Journal
Biochem J (2015) 470 (2): 207–221.
Published: 20 August 2015
...) and uncoordinated-51-like kinase (ULK1), which results in increased autophagic flux and reduced cellular proliferation. 1 To whom correspondence should be addressed (email [email protected] ). 1 4 2015 8 7 2015 9 7 2015 9 7 2015 © 2015 Authors 2015 This is an open access...
Includes: Supplementary data
Articles
Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis
Available to PurchaseAndrew J. O’Brien, Linda A. Villani, Lindsay A. Broadfield, Vanessa P. Houde, Sandra Galic, Giovanni Blandino, Bruce E. Kemp, Theodoros Tsakiridis, Paola Muti, Gregory R. Steinberg
Journal:
Biochemical Journal
Biochem J (2015) 469 (2): 177–187.
Published: 06 July 2015
...-glutaryl (HMG)-CoA reductase aspirin cholesterol fatty acids mammalian target of rapamycin (mTOR) acetyl-CoA carboxylase (ACC) proliferation Daily aspirin ingestion reduces the risk of death from adenocarcinomas of the colon, lung and prostate [ 1 , 2 ]. Although the anti-tumour effects...
Articles
HBx induces the proliferation of hepatocellular carcinoma cells via AP1 over-expressed as a result of ER stress
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2015) 466 (1): 115–121.
Published: 06 February 2015
... in the liver. In the present study, we address the role played by CREBH activated by ER stress in HBV-induced hepatic cell proliferation. We confirmed CREBH activation by ER stress and showed that it occurred as a result of/via hepatitis B virus X (HBx)-induced ER stress. CREBH activated by HBx increased...
Articles
YB-1: oncoprotein, prognostic marker and therapeutic target?
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2013) 449 (1): 11–23.
Published: 07 December 2012
... regulates multiple proliferation pathways, overrides cell-cycle check points, promotes replicative immortality and genomic instability, may regulate angiogenesis, has a role in invasion and metastasis, and promotes inflammation. We also argue that there is strong and sufficient evidence to suggest that YB-1...
Articles
Protein arginine methyltransferase 5 is essential for growth of lung cancer cells
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2012) 446 (2): 235–241.
Published: 14 August 2012
... in benign lung tissues. Silencing PRMT5 expression strongly inhibited proliferation of lung adenocarcinoma A549 cells in tissue culture, and silencing PRMT5 expression in A549 cells also abolished growth of lung A549 xenografts in mice. In vitro and in vivo studies showed that the cell growth arrest induced...
Articles
The mouse Mageb18 gene encodes a ubiquitously expressed type I MAGE protein and regulates cell proliferation and apoptosis in melanoma B16-F0 cells
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2012) 443 (3): 779–788.
Published: 16 April 2012
... The Authors Journal compilation © 2012 Biochemical Society 2012 apoptosis cancer immunotherapy epigenetic regulation expression pattern melanoma antigen family B 18 (Mageb18) proliferation subcellular localization To date, more than 120 MAGE (melanoma antigen) genes and pseudogenes have...
Includes: Supplementary data
Articles
Regulation and function of the RSK family of protein kinases
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2012) 441 (2): 553–569.
Published: 21 December 2011
...Yves Romeo; Xiaocui Zhang; Philippe P. Roux The RSK (90 kDa ribosomal S6 kinase) family comprises a group of highly related serine/threonine kinases that regulate diverse cellular processes, including cell growth, proliferation, survival and motility. This family includes four vertebrate isoforms...
Articles
Vitamin D and cancer: a review of molecular mechanisms
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2012) 441 (1): 61–76.
Published: 14 December 2011
... (25OH D) proliferation transcription vitamin D receptor Over the past decade, researchers have generated data demonstrating that vitamin D and its metabolites have actions that may be useful for the prevention or treatment of various cancers. This is a new role for vitamin D that is distinct...
Articles
Retinaldehyde is a substrate for human aldo–keto reductases of the 1C subfamily
Available to PurchaseF. Xavier Ruiz, Sergio Porté, Oriol Gallego, Armando Moro, Albert Ardèvol, Alberto Del Río-Espínola, Carme Rovira, Jaume Farrés, Xavier Parés
Journal:
Biochemical Journal
Biochem J (2011) 440 (3): 335–347.
Published: 28 November 2011
... aldo–keto reductase (AKR) retinaldehyde retinoic acid retinol proliferation Retinol (vitamin A) and its derivatives retinaldehyde and RA (retinoic acid) are essential for the formation and maintenance of many body tissues, such as skin, bone and the vasculature, as well as for the visual...
Includes: Supplementary data
Articles
Adhesion-dependent Skp2 transcription requires selenocysteine tRNA gene transcription-activating factor (STAF)
Available to PurchaseIvette Hernández-Negrete, Graciela B. Sala-Newby, Andras Perl, Gary R. Kunkel, Andrew C. Newby, Mark Bond
Journal:
Biochemical Journal
Biochem J (2011) 436 (1): 133–143.
Published: 27 April 2011
... activity and expression and STAF siRNA (small interfering RNA) inhibits Skp2 promoter activity, mRNA and protein expression and cell proliferation. Furthermore, ectopic Skp2 expression completely reverses the inhibitory effects of STAF silencing on proliferation. Importantly, STAF expression and binding...
Includes: Supplementary data
Articles
Cell surface heparan sulfates mediate internalization of the PWWP/HATH domain of HDGF via macropinocytosis to fine-tune cell signalling processes involved in fibroblast cell migration
Available to PurchaseChia-Hui Wang, Fabian Davamani, Shih-Che Sue, Shao-Chen Lee, Po-long Wu, Fan-Mei Tang, Chiaho Shih, Tai-huang Huang, Wen-guey Wu
Journal:
Biochemical Journal
Biochem J (2011) 433 (1): 127–138.
Published: 15 December 2010
...Chia-Hui Wang; Fabian Davamani; Shih-Che Sue; Shao-Chen Lee; Po-long Wu; Fan-Mei Tang; Chiaho Shih; Tai-huang Huang; Wen-guey Wu HDGF (hepatoma-derived growth factor) stimulates cell proliferation by functioning on both sides of the plasma membrane as a ligand for membrane receptor binding...
Includes: Supplementary data
Articles
MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells
Available to PurchaseLu Jiang, Xiqiang Liu, Zujian Chen, Yi Jin, Caroline E. Heidbreder, Antonia Kolokythas, Anxun Wang, Yang Dai, Xiaofeng Zhou
Journal:
Biochemical Journal
Biochem J (2010) 432 (1): 199–207.
Published: 25 October 2010
...Lu Jiang; Xiqiang Liu; Zujian Chen; Yi Jin; Caroline E. Heidbreder; Antonia Kolokythas; Anxun Wang; Yang Dai; Xiaofeng Zhou miR-7 (microRNA-7) has been characterized as a tumour suppressor in several human cancers. It targets a number of proto-oncogenes that contribute to cell proliferation...
Includes: Supplementary data
Articles
c-Jun N-terminal kinase/c-Jun inhibits fibroblast proliferation by negatively regulating the levels of stathmin/oncoprotein 18
Available to PurchaseYvonne Y. C. Yeap, Ivan H. W. Ng, Bahareh Badrian, Tuong-Vi Nguyen, Yan Y. Yip, Amardeep S. Dhillon, Steven E. Mutsaers, John Silke, Marie A. Bogoyevitch, Dominic C. H. Ng
Journal:
Biochemical Journal
Biochem J (2010) 430 (2): 345–354.
Published: 13 August 2010
... proliferation. We have developed a cell system to control JNK re-expression at physiological levels in JNK1/2 -null MEFs (murine embryonic fibroblasts). JNK re-expression restored basal and stress-activated phosphorylation of the c-Jun transcription factor and attenuated cellular proliferation with increased...
Includes: Supplementary data
Articles
Role of cellular bioenergetics in smooth muscle cell proliferation induced by platelet-derived growth factor
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2010) 428 (2): 255–267.
Published: 13 May 2010
...Jessica Perez; Bradford G. Hill; Gloria A. Benavides; Brian P. Dranka; Victor M. Darley-Usmar Abnormal smooth muscle cell proliferation is a hallmark of vascular disease. Although growth factors are known to contribute to cell hyperplasia, the changes in metabolism associated with this response...
Includes: Supplementary data
Articles
Functional characterization of ribosomal P1/P2 proteins in human cells
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2008) 413 (3): 527–534.
Published: 15 July 2008
... cytoplasmic translation by influencing the interaction between subunits, thereby regulating the rate of cell proliferation. 1 To whom correspondence should be addressed (email [email protected] ). 8 1 2008 17 3 2008 18 4 2008 18 4 2008 © The Authors Journal compilation ©...
Includes: Supplementary data
Articles
The zinc finger transcription factor ZFHX1A is linked to cell proliferation by Rb–E2F1
Available to PurchaseYongqing Liu, Mary E. Costantino, Diego Montoya-Durango, Yujiro Higashi, Douglas S. Darling, Douglas C. Dean
Journal:
Biochemical Journal
Biochem J (2007) 408 (1): 79–85.
Published: 29 October 2007
...Yongqing Liu; Mary E. Costantino; Diego Montoya-Durango; Yujiro Higashi; Douglas S. Darling; Douglas C. Dean ZFHX1A is expressed in proliferating cells in the developing embryo, and in the present study we provide evidence that its expression is confined to proliferating cells through dependence...
Includes: Supplementary data
Articles
Prolactin stimulates prostate cell proliferation by increasing endoplasmic reticulum content due to SERCA 2b over-expression
Available to PurchaseAlexandre Crépin, Gabriel Bidaux, Fabien Vanden-Abeele, Etienne Dewailly, Vincent Goffin, Natalia Prevarskaya, Christian Slomianny
Journal:
Biochemical Journal
Biochem J (2007) 401 (1): 49–55.
Published: 11 December 2006
...Alexandre Crépin; Gabriel Bidaux; Fabien Vanden-Abeele; Etienne Dewailly; Vincent Goffin; Natalia Prevarskaya; Christian Slomianny Prolactin (PRL) has been shown to be involved in the differen-tiation and proliferation of numerous tissues, including the prostate gland. Moreover, variations in [Ca 2...
Articles
Sphingosine 1-phosphate receptor expression profile and regulation of migration in human thyroid cancer cells
Available to PurchaseSonja Balthasar, Johanna Samulin, Hanna Ahlgren, Nina Bergelin, Mathias Lundqvist, Emil C. Toescu, Margaret C. Eggo, Kid Törnquist
Journal:
Biochemical Journal
Biochem J (2006) 398 (3): 547–556.
Published: 29 August 2006
... (FRO, ARO) thyroid cancer cell lines, as well as in human thyroid cells in primary culture. Additionally, the effects of S1P on proliferation, adhesion and calcium signalling were addressed in ML-1 and FRO cells. All cell types expressed multiple S1P receptors. S1P evoked intracellular calcium...
Articles
The spot 14 protein inhibits growth and induces differentiation and cell death of human MCF-7 breast cancer cells
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2005) 390 (1): 57–65.
Published: 09 August 2005
... of these kinds of tumours. In the present study, we have examined the effects of S14 overexpression in MCF-7 human breast cancer cells. We found that S14 causes (i) an inhibition of cell proliferation and of anchorage-independent growth, (ii) a marked reduction in the number of viable cells and (iii...
Articles
Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter
Available to PurchaseRémy Nyga, Christian Pecquet, Noria Harir, Haihua Gu, Isabelle Dhennin-Duthille, Aline Régnier, Valérie Gouilleux-Gruart, Kaïss Lassoued, Fabrice Gouilleux
Journal:
Biochemical Journal
Biochem J (2005) 390 (1): 359–366.
Published: 09 August 2005
... with interleukin-3 or expressing the oncogenic fusion protein Tel–JAK2. The MAPKs (mitogen-activated protein kinases) ERK1 (extracellular-signal-regulated kinase 1) and ERK2 were constitutively activated in the ca STAT5-expressing cells and were found to be required for ca STAT5-induced cell proliferation...
Articles
The flip side of FLIP
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2004) 382 (2): e1.
Published: 24 August 2004
... apoptosis and proliferation, as found in many diseases. Figure 1 Model of the different functions of c-FLIP L Shown is the CD95 DISC at different concentrations of c-FLIP L . In the absence of c-FLIP L (no FLIP), both procaspase-8 (C8) and procaspase-10 (C10) are recruited to the DISC through...
Articles
CCAAT/enhancer-binding proteins: structure, function and regulation
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2002) 365 (3): 561–575.
Published: 01 August 2002
... of the C/EBPs has recently been investigated by a number of approaches, including studies on mice that lack specific members, and has identified pivotal roles of the family in the control of cellular proliferation and differentiation, metabolism, inflammation and numerous other responses, particularly...
Articles
γ-Glutamyl transpeptidase expression in Ewing's sarcoma cells:up-regulation by interferons
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2002) 364 (3): 719–724.
Published: 15 June 2002
... correspondence should be addressed (e-mail [email protected] ). 19 12 2001 27 2 2002 8 4 2002 The Biochemical Society, London ©2002 2002 cancer ectopeptidase proliferation Abbreviations used: ET, Ewing's sarcoma family of tumours; EWS, Ewing's sarcoma gene; IFN...
Articles
Mitogen-activated protein kinases control p27/Kip1 expression and growth of human melanoma cells
Available to PurchaseMarcin KORTYLEWSKI, Peter C. HEINRICH, Maria-Elisabeth KAUFFMANN, Markus BÖHM, Andrzej MACKIEWICZ, Iris BEHRMANN
Journal:
Biochemical Journal
Biochem J (2001) 357 (1): 297–303.
Published: 25 June 2001
...-mail [email protected] ). 22 2 2001 26 3 2001 20 4 2001 The Biochemical Society, London ©2001 2001 PD098059 proliferation protein stability Abbreviations used: Cdk, cyclin-dependent kinase; ERK, extracellular signal-regulated protein kinase; GAPDH, glyceraldehyde-3...
Articles
5-Hydroxytryptamine1A receptor/Giβγ stimulates mitogen-activated protein kinase via NAD(P)H oxidase and reactive oxygen species upstream of Src in Chinese hamster ovary fibroblasts
Available to PurchaseYurii V. MUKHIN, Maria N. GARNOVSKAYA, Georgiann COLLINSWORTH, Jasjit S. GREWAL, DeKisha PENDERGRASS, Toshio NAGAI, Stephen PINCKNEY, Eddie L. GREENE, John R. RAYMOND
Journal:
Biochemical Journal
Biochem J (2000) 347 (1): 61–67.
Published: 27 March 2000
... proliferation serotonin receptor tyrosine kinase Biochem. J. (2000) 347, 61 67 (Printed in Great Britain) 61 5-Hydroxytryptamine1A receptor/Gibc stimulates mitogen-activated protein kinase via NAD(P)H oxidase and reactive oxygen species upstream of Src in Chinese hamster ovary fibroblasts Yurii V. MUKHIN...
Articles
Sphingosine 1-phosphate stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle
Available to Purchase
Journal:
Biochemical Journal
Biochem J (1999) 338 (3): 643–649.
Published: 08 March 1999
... , [email protected] ). 18 8 1998 27 10 1998 5 1 1999 The Biochemical Society, London © 1999 1999 lipid kinases proliferation Ras sphingolipids Biochem. J. (1999) 338, 643 649 (Printed in Great Britain) 643 Sphingosine 1-phosphate stimulation of the p42/p44 mitogen...
