1-13 of 13
Keywords: prostate cancer
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biochem J (2021) 478 (15): 2999–3014.
Published: 10 August 2021
... 2021 ADP-ribosylation androgen receptor mono-ADP-ribosyltransferase PARP7 prostate cancer TIPARP More than 1.2 million men in the world were diagnosed with prostate cancer (PCa) in 2018, making it the second most frequently diagnosed cancer in men and a disease that contributes...
Articles
Biochem J (2016) 473 (15): 2331–2343.
Published: 28 July 2016
.../molecules that control WDR77 gene expression are unknown. Promoter mapping, gel shift assay and ChIP revealed that the WDR77 promoter contains bona fide response elements for E2F and GATA transcriptional factors as demonstrated in prostate cancer, lung cancer and erythroid cells, as well as in mouse lung...
Includes: Supplementary data
Articles
Biochem J (2016) 473 (4): 449–461.
Published: 09 February 2016
...), prostate cancer cells (PC-3, DU-145, 22Rv1 and LNCaP) and human normal or tumour tissue was assessed by bisulfite sequencing analysis, and then confirmed by COBRA (combined bisulfite restriction analysis) and qAMP (quantitative analysis of DNA methylation using real-time PCR). These results demonstrated...
Includes: Supplementary data
Articles
Biochem J (2013) 453 (1): 125–136.
Published: 13 June 2013
... be addressed (email gelmanne@columbia.edu ). 3 1 2013 23 3 2013 5 4 2013 5 4 2013 © The Authors Journal compilation © 2013 Biochemical Society 2013 camptothecin (CPT) DNA repair homeodomain NK3 homeobox 1 (NKX3.1) prostate cancer topoisomerase I NKX3.1 (NK3...
Articles
Biochem J (2012) 446 (2): 191–201.
Published: 14 August 2012
...James R. Krycer; Lisa Phan; Andrew J. Brown There is growing evidence showing that prostate cancer cells have perturbed cholesterol homoeostasis, accumulating cholesterol to promote cell growth. Consequently, cholesterol-lowering drugs such as statins are being evaluated in prostate cancer...
Includes: Supplementary data
Articles
Biochem J (2012) 445 (1): 135–144.
Published: 15 June 2012
... the membrane proximal cysteine-rich extension of the ADAM17 protein. Unlike normal cells, tumour cell lines, such as a prostate cancer cell line, pancreatic cancer cell lines, a breast cancer cell line and a non-small lung cancer cell line, expressed ADAM17 on the cell surface. Using the sequence...
Includes: Supplementary data
Articles
Biochem J (2012) 442 (3): 483–494.
Published: 24 February 2012
... is a type II transmembrane serine protease that is expressed in several human tissues. Overexpression of hepsin has been found to correlate with tumour progression and metastasis, which is so far best studied for prostate cancer, where more than 90% of such tumours show this characteristic. To enable...
Includes: Supplementary data
Articles
Biochem J (2011) 433 (1): 225–233.
Published: 15 December 2010
...Jong-Seok Moon; Won-Ji Jin; Jin-Hye Kwak; Hyo-Jeong Kim; Mi-Jin Yun; Jae-Woo KIM; Sahng Wook Park; Kyung-Sup Kim Up-regulation of lipogenesis by androgen is one of the most characteristic metabolic features of LNCaP prostate cancer cells. The present study revealed that androgen increases glucose...
Includes: Supplementary data
Articles
Biochem J (2011) 433 (1): 235–244.
Published: 15 December 2010
...Kyung-Chul Choi; SiYong Park; Beom Jin Lim; Ah-Reum Sung; Yoo-Hyun Lee; Masaki Shiota; Akira Yokomizo; Seiji Naito; Younghwa Na; Ho-Geun Yoon Increasing evidence suggests that AR (androgen receptor) acetylation is critical for prostate cancer cell growth. In the present study, we identified Pro-B3...
Includes: Supplementary data
Articles
Biochem J (2010) 425 (3): 575–583.
Published: 15 January 2010
...Marc A. Thomas; Darren M. Preece; Jacqueline M. Bentel The homeodomain transcription factor NKX3.1 is a prostate-specific tumour suppressor, expression of which is reduced or undetectable in the majority of metastatic prostate tumours. In the normal prostate and in prostate cancer cells, NKX3.1...
Articles
Biochem J (2005) 388 (3): 967–972.
Published: 07 June 2005
... and malignant cell types. Previous in vitro studies on prostate cancer cells suggest a role for PAR-2 in prostate cancer metastasis. A polyclonal anti-human TMPRSS2 antibody was generated against the TMPRSS2 serine protease domain. The antibody showed specific reactivity with recombinant expressed TMPRSS2...
Articles
Biochem J (2004) 382 (1): 157–168.
Published: 10 August 2004
... should be addressed (email saverio.bettuzzi@unipr.it ). 28 1 2004 15 4 2004 12 5 2004 12 5 2004 The Biochemical Society, London 2004 anoikis apoptosis caspase clusterin PNT1A cell prostate cancer Clusterin is a glycoprotein widely distributed in mammalian...
Articles
Biochem J (2003) 375 (2): 373–383.
Published: 15 October 2003
... of DDC in prostate cancer cells strongly enhanced ligand-dependent AR transcriptional activity, an effect that was antagonized using high concentrations of the anti-androgen bicalutamide. Glucocorticoid receptor activity was also strongly enhanced with DDC co-transfection, while oestrogen receptor...