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Keywords: protein–DNA complex
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Articles
DNA topology influences p53 sequence-specific DNA binding through structural transitions within the target sites
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2008) 412 (1): 57–63.
Published: 25 April 2008
...–DNA complex p53 supercoil topoisomer The p53 tumour suppressor protein is an important transcription factor that induces cell-cycle arrest or apoptosis in response to oncogenic transformation and DNA damage. Point mutations and deletions in the p53 gene are the most frequently observed...