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Keywords: protein–peptide interactions
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Biochem J (2021) 478 (11): 2145–2161.
Published: 11 June 2021
... of ∼120 nM to WDR5 [ 22 ]. k on values measured by SPR are yet at least an order of magnitude lower than those predicted for a proteinpeptide interaction system (10 7 –10 8  M −1  s −1 ) [ 84–88 ]. Here, WDR5-SET1 Win interactions require a precise insertion of the six-residue, Arg...
Includes: Supplementary data