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Keywords: protein trafficking
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Articles
Biochem J (2020) 477 (13): 2561–2580.
Published: 10 July 2020
... behalf of the Biochemical Society 2020 actin cytoskeleton cAMP CFTR EPAC1 protein trafficking Cystic Fibrosis (CF) is the most common lethal and life-limiting autosomic recessive disorder among Caucasian population, affecting about 1 : 2500–6000 new borns [ 1 ] and it is caused by...
Includes: Supplementary data
Articles
Biochem J (2017) 474 (18): 3167–3177.
Published: 08 September 2017
... behalf of the Biochemical Society 2017 irisin secretion N-linked glycosylation protein stabilization protein trafficking FNDC5 (fibronectin type III domain-containing protein 5) is a protein that in mice consists of 209 amino acids (AAs). It includes four parts, namely an N-terminal 28...
Articles
Biochem J (2017) 474 (15): 2573–2584.
Published: 18 July 2017
...) exchanger 1 (kAE1) can cause genetic distal renal tubular acidosis (dRTA). Different SLC4A1 mutations give rise to mutant kAE1 proteins with distinct defects in protein trafficking. The mutant kAE1 protein may be retained in endoplasmic reticulum (ER) or Golgi apparatus, or mis-targeted to the apical...
Articles
Biochem J (2016) 473 (7): 919–928.
Published: 29 March 2016
... many other membrane proteins, its intracellular sorting and distribution have a tremendous effect on its function, and constitute an important aspect of its regulation. Many short sequences have been shown to contribute to protein trafficking along the sorting or endocytic pathways. Using...
Includes: Supplementary data
Articles
Biochem J (2014) 460 (2): 295–307.
Published: 13 May 2014
... migration protein trafficking The PLG/PLA (plasminogen/plasmin) system has been linked to a variety of pericellular proteolytic processes in embryonic development [ 1 ], monocyte/macrophage recruitment [ 2 , 3 ], wound healing [ 4 , 5 ], angiogenesis [ 4 , 6 ] and tumour cell invasion [ 7 – 9...
Includes: Supplementary data
Articles
Biochem J (2014) 459 (2): 417–425.
Published: 28 March 2014
... important defects in cystic fibrosis should consider the role of palmitoylation as a molecular target. cystic fibrosis palmitoylation post-translational modification protein trafficking protein maturation CF (cystic fibrosis) is a disease caused by mutations of the CFTR (CF transmembrane...
Includes: Supplementary data
Articles
Biochem J (2013) 454 (1): 69–77.
Published: 26 July 2013
... might explain the variability in the trafficking defect caused by each mutant. genotype–phenotype relationship human ethera-go-go -related gene KCNH2 long-QT syndrome protein trafficking Loss-of-function mutations in membrane-spanning proteins usually result in protein misfolding...
Includes: Supplementary data
Articles
Biochem J (2012) 447 (1): 51–60.
Published: 12 September 2012
... effects were observed in cells enriched with lipoprotein-derived cholesterol and in primary human macrophages. Removal of excess cholesterol by a cyclodextrin vehicle restored apoE secretion, indicating that the transport defect was reversible. That cholesterol impaired protein trafficking was supported...
Includes: Supplementary data
Articles
Biochem J (2010) 425 (2): 341–351.
Published: 23 December 2009
..., distribution and reproduction in any medium, provided the original work is properly cited. doppel (Dpl) epithelial cell lipid raft prion protein (PrP) protein trafficking The PrP C (cellular prion protein) is a cell-surface glycoprotein of unknown function expressed in mammalian tissues...
Includes: Supplementary data
Articles
Biochem J (2009) 419 (1): 211–221.
Published: 13 March 2009
... protein trafficking. We thank J.R. Riordan (University of North Carolina at Chapel Hill, Chapel Hill, NC, U.S.A.) for providing the anti-CFTR mAb 450. AM acetoxymethyl ester BHK baby-hamster kidney CF cystic fibrosis CFBE CF bronchial epithelial CFTR CF transmembrane...
Includes: Supplementary data
Articles
Biochem J (2007) 407 (3): 343–354.
Published: 12 October 2007
... 8 2007 14 8 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 digestive vacuole green fluorescent protein (GFP) pH plasmepsin Plasmodium falciparum protein trafficking The malaria parasite spends part of its life cycle inside the RBCs (red blood...
Includes: Supplementary data
Articles
Biochem J (2007) 405 (1): 147–155.
Published: 13 June 2007
... 5 2006 14 2 2007 23 3 2007 23 3 2007 © 2007 Biochemical Society 2007 endocytosis kidney Liddle's syndrome neuronal precursor cell expressed developmentally down-regulated gene 4-2 (Nedd4-2) protein trafficking ubiquitin The ENaC (epithelial sodium channel) is...
Articles
Biochem J (2004) 380 (1): 43–49.
Published: 15 May 2004
... export (ER export) prenylated Rab acceptor 1 (PRA1) prenylin protein trafficking Yip3 Abbreviations used: BHK, baby hamster kidney; BMH, bismaleimidohexane; DSS, disuccinyl suberate; ER, endoplasmic reticulum; GFP, green fluorescent protein; Man II, mannosidase II; WT, wild-type; D176A etc...
Articles
Biochem J (2003) 371 (2): 533–540.
Published: 15 April 2003
... LSB6 phosphoinositide protein trafficking yeast Abbreviations used: GAPDH, glyceraldehyde-3-phosphate dehydrogenase; GFP, green fluorescent protein; HA, haemagglutinin; LSB6 , L a s 17p- b inding protein; ORF, open reading frame; PI 4-kinase, phosphoinositide 4-kinase; PI4KII, PI 4...
Articles
Biochem J (2002) 365 (3): 693–699.
Published: 01 August 2002
... assembly membrane integration protein trafficking Abbreviations used: Cx, connexin; DTT, dithiothreitol; TEA, triethanolamine. Biochem. J. (2002) 365, 693 699 (Printed in Great Britain) 693 Post-translational integration and oligomerization of connexin 26 in plasma membranes and evidence of...
Articles
Biochem J (2001) 355 (3): 725–731.
Published: 24 April 2001
... (e-mail stefan.broeer@anu.edu.au ). 15 11 2000 24 1 2001 19 2 2001 The Biochemical Society, London © 2001 2001 amino acid transport heterodimeric transporter protein trafficking Biochem. J. (2001) 355, 725 731 (Printed in Great Britain) 725 Association of 4F2hc with...
Articles
Biochem J (2001) 355 (3): 617–624.
Published: 24 April 2001
..., U.S.A. 3 To whom correspondence should be addressed (e-mail josh.hamilton@dartmouth.edu ). 27 10 2000 8 1 2001 14 2 2001 The Biochemical Society, London © 2001 2001 ATP-binding cassette protein multidrug resistance protein trafficking Biochem. J. (2001) 355, 617...
Articles
Biochem J (2000) 351 (1): 115–122.
Published: 26 September 2000
... to GenBank under the accession numbers AF230802 and AF230803 respectively. 1 To whom correspondence should be addressed (e-mail guderman@mailer.uni-marburg.de ). 24 2 2000 23 6 2000 19 7 2000 The Biochemical Society, London © 2000 2000 calcium protein trafficking...
Articles
Biochem J (2000) 346 (2): 329–336.
Published: 22 February 2000
... 2000 internalization protein trafficking zinc uptake Biochem. J. (2000) 346, 329 336 (Printed in Great Britain) 329 Zinc-regulated ubiquitin conjugation signals endocytosis of the yeast ZRT1 zinc transporter Raad S. GITAN and David J. EIDE1 Department of Nutritional Sciences, 217 Gwynn Hall...