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Biochem J (2014) 460 (2): 187–198.
Published: 13 May 2014
... interaction plant defence protease proteinase The cleavage site specificity of Bz-cmp and Es-cmp was determined by MALDI–TOF-MS analysis of the peptide products. Bz-cmp was incubated with either ChitA-B73, ChitA-LH82 or ChitB and the product peptides were detected by MS analysis ( Figure 3 A...
Biochem J (2012) 447 (3): 335–351.
Published: 05 October 2012
... 7 2012 23 7 2012 © The Authors Journal compilation © 2012 Biochemical Society 2012 calcium-binding domain structure enzyme activation inhibitor complex proteinase proteolysis X-ray crystallography The present review will focus on insights about calpains and their...
Includes: Multimedia, Supplementary data
Biochem J (2007) 407 (2): 153–159.
Published: 25 September 2007
... metastasis at the time of diagnosis. Recent genome-wide screening efforts have identified the serine proteinase uPA (urinary-type plasminogen activator, also known as urokinase) as a strong biomarker for prediction of poor disease outcome and a key candidate for molecular classification of oral neoplasms...
Sergey A. Shiryaev, Boris I. Ratnikov, Alexei V. Chekanov, Sergey Sikora, Dmitri V. Rozanov, Adam Godzik, Jun Wang, Jeffrey W. Smith, Ziwei Huang, Iris Lindberg, Melanie A. Samuel, Michael S. Diamond, Alex Y. Strongin
Biochem J (2006) 393 (2): 503–511.
Published: 23 December 2005
... proteinase, which is essential for the proteolytic processing of the viral polyprotein precursor, is a promising drug target. We have isolated and biochemically characterized the recombinant, highly active NS3 proteinase. We have determined that the NS3 proteinase functions in a manner that is distantly...
Biochem J (2003) 373 (1): 19–24.
Published: 01 July 2003
...) proteinase proteinase inhibitor tissue inhibitor of matrix metalloproteinases 2 (TIMP-2) tumour cell Abbreviations used: bafilo, bafilomycin-A 1 ; DMEM, Dulbecco's modified Eagle's medium; mAb, monoclonal antibody; MMP, matrix metalloproteinase; MT-MMP, membrane-type MMP; TIMP, tissue inhibitor...
Biochem J (2002) 368 (1): 365–369.
Published: 15 November 2002
... should be addressed (e-mail email@example.com ). 29 5 2002 12 8 2002 29 8 2002 29 8 2002 The Biochemical Society, London ©2002 2002 fluorescent peptide fluorogenic substrate proteinase thiol protease Abbreviations used: Abz, o -aminobenzoic acid; Dap(Dnp...
Ajay SINGH, Bhaskar R. SHENAI, Youngchool CHOE, Jiri GUT, Puran S. SIJWALI, Charles S. CRAIK, Philip J. ROSENTHAL
Biochem J (2002) 368 (1): 273–281.
Published: 15 November 2002
... will appear in GenBank ® EMBL, DDBJ and GSDB Nucleotide Sequence Databases under accession nos. AY063763 and AY063764. 10 5 2002 24 7 2002 8 8 2002 8 8 2002 The Biochemical Society, London ©2002 2002 falcipain haemoglobin Plasmodium proteinase...
Biochem J (2001) 358 (3): 615–626.
Published: 10 September 2001
... ©2001 2001 glycosaminoglycan osteoarthritis proteinase Abbreviations used: ADAMTS, a disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif; MMP, matrix metalloproteinase; G1 domain, the N-terminal globular domain of aggrecan; G2 domain, the second N...
Marc A. LAFLEUR, Morley D. HOLLENBERG, Susan J. ATKINSON, Vera KNÄUPER, Gillian MURPHY, Dylan R. EDWARDS
Biochem J (2001) 357 (1): 107–115.
Published: 25 June 2001
... in the presence of cells. Thrombin also rapidly (within 1h) increased cellular MT-MMP activity, and at longer time points (>6h) it increased expression of MT1-MMP mRNA and protein. Thus signalling via proteinase-activated receptors (PARs) may play a role in thrombin-induced MMP-2 activation...
Biochem J (2000) 349 (2): 473–479.
Published: 10 July 2000
... [McKenna, Liu, Sansom and Dean (1998) Arthritis Rheum. 41, 157-161]. The mechanism by which this biologically active peptide is degraded and inactivated was investigated using U937 monocytes as a model cell. Time-course experiments showed that two major proteases, an initial serine proteinase followed by a...
Piers NASH, Michele BARRY, Bruce T. SEET, Kirstin VEUGELERS, Susy HOTA, Jody HEGER, Carley HODGKINSON, Kathryn GRAHAM, Ronald J. JACKSON, Grant MCFADDEN
Biochem J (2000) 347 (2): 375–382.
Published: 10 April 2000
...Piers NASH; Michele BARRY; Bruce T. SEET; Kirstin VEUGELERS; Susy HOTA; Jody HEGER; Carley HODGKINSON; Kathryn GRAHAM; Ronald J. JACKSON; Grant MCFADDEN SERP-1 is a secreted serpin (serine-proteinase inhibitor) encoded by myxoma virus, a poxvirus pathogen of rabbits. SERP-1 is required for myxoma...