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Keywords: pyridoxal-5′-phosphate
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Duaa W. Al-Sadeq, Carolina Conter, Angelos Thanassoulas, Nader Al-Dewik, Bared Safieh-Garabedian, Luis Alfonso Martínez-Cruz, Gheyath K. Nasrallah, Alessandra Astegno, Michail Nomikos
Journal:
Biochemical Journal
Biochem J (2024) 481 (8): 569–585.
Published: 22 April 2024
... β-synthase (CBS). CBS is an essential pyridoxal 5′-phosphate (PLP)-dependent enzyme in the transsulfuration pathway, responsible for combining serine with homocysteine to produce cystathionine, whose activity is enhanced by the allosteric regulator S -adenosylmethionine (SAM). CBS also plays a role...
Includes: Supplementary data