1-19 of 19
Keywords: receptor tyrosine kinase
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Articles
Biochem J (2012) 447 (1): 1–16.
Published: 12 September 2012
... phosphotyrosine signalling phosphotyrosine-binding domain (PTB domain) receptor tyrosine kinase signal transduction Src homology and collagen homology (Shc) Src homology 2 domain (SH2 domain) Fundamentally, the ability of Shc proteins to engage in controlled signal propagation in a given cell...
Articles
Biochem J (2012) 445 (1): 47–56.
Published: 15 June 2012
...Ilaria Lamberto; Haina Qin; Roberta Noberini; Lakshmanane Premkumar; Caroline Bourgin; Stefan J. Riedl; Jianxing Song; Elena B. Pasquale The EphA4 receptor tyrosine kinase interacts with ephrin ligands to regulate many processes, ranging from axon guidance and nerve regeneration to cancer...
Includes: Supplementary data
Articles
Articles
Biochem J (2011) 437 (2): 199–213.
Published: 28 June 2011
... growth factor (FGF) fibroblast growth factor receptor (FGFR) receptor tyrosine kinase signalling therapy Human cancers usually develop through a multi-stage process that may extend over decades. During cancer development, normal cells are progressively transformed into highly malignant...
Includes: Multimedia, Supplementary data
Articles
Biochem J (2009) 423 (3): 375–380.
Published: 12 October 2009
...Christina Wehrle; Paul Van Slyke; Daniel J. Dumont Tie2 [where ‘Tie’ is an acronym from t yrosine kinase with I g and E GF (epidermal growth factor) homology domains] is a receptor tyrosine kinase expressed predominantly on the surface of endothelial cells. Activated by its ligands...
Articles
Biochem J (2009) 422 (3): 433–442.
Published: 27 August 2009
...Nicole K. Noren; Nai-Ying Yang; Morgan Silldorff; Ravi Mutyala; Elena B. Pasquale Receptor tyrosine kinases of the Eph family become tyrosine phosphorylated and initiate signalling events upon binding of their ligands, the ephrins. Eph receptors such as EphA2 and EphB4 are highly expressed...
Includes: Supplementary data
Articles
Biochem J (2008) 415 (2): 241–245.
Published: 25 September 2008
... To whom correspondence should be addressed (email [email protected] ). 15 1 2008 26 6 2008 30 6 2008 30 6 2008 © The Authors Journal compilation © 2008 Biochemical Society 2008 adaptor protein c-Kit Lnk protein–protein interaction receptor tyrosine kinase signal...
Articles
Articles
Biochem J (2006) 393 (1): 235–243.
Published: 12 December 2005
... Society, London 2006 mathematical modelling phosphoinositide 3-kinase (PI3K) platelet-derived growth factor (PDGF) Ras receptor tyrosine kinase signal transduction 1 These authors contributed equally to this work. 2 To whom correspondence should be addressed (email...
Includes: Supplementary data
Articles
Articles
Biochem J (2005) 391 (2): 153–166.
Published: 10 October 2005
... Society, London 2005 Cbl E3 ligase receptor tyrosine kinase T-cell receptor thymocyte ubiquitin The mammalian Cbl family of proteins consists of three homologues known as c-Cbl, Cbl-b and Cbl-3 ( Figure 1 ). All three share highly conserved regions in their N-terminal halves which...
Articles
Articles
Biochem J (2004) 380 (1): e11–e12.
Published: 15 May 2004
...Craig C. MALBON Cell signalling via receptor tyrosine kinases, such as the insulin receptor, and via heterotrimeric G-proteins, such as Gα i , Gα s and Gα q family members, constitute two of most avidly studied paradigms in cell biology. That elements of these two populous signalling pathways must...
Articles
Biochem J (2003) 376 (3): 587–594.
Published: 15 December 2003
... factor receptor. Key words: Akt/protein serine/threonine kinase B (PKB), macrophage-stimulating protein (MSP), protein phosphatase, protein phosphorylation, receptor tyrosine kinase, Ron. INTRODUCTION Receptor tyrosine kinases (RTKs) can be regulated by PTPs (protein tyrosine phosphatases [1]) in many...
Articles
Articles
Articles
Articles
Biochem J (2000) 345 (1): 107–113.
Published: 17 December 1999
... signalling of receptor tyrosine kinases. Receptor dimerization leads to an increase in kinase activity, resulting in autophosphorylation and the induction of diverse biological Abbreviations used: FGF, fibroblast growth factor ; FGFR, FGF receptor ; FGF1 (aFGF), acidic FGF; FGF2 (bFGF), basic FGF; DSS...
Articles
Biochem J (1999) 342 (1): 163–170.
Published: 10 August 1999
...Sherry MOU; Diana LINNEKIN Stem cell factor (SCF) binds the receptor tyrosine kinase c-Kit and is critical in haemopoiesis. Recently we found that the Src family member Lyn is highly expressed in SCF-responsive cells, associates with c-Kit and is activated within minutes of the addition of SCF...