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Keywords: redox-switch
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Biochem J (2021) 478 (17): 3319–3330.
Published: 14 September 2021
... by modulating the release of angiotensin peptides that control blood pressure. One mechanism by which this modulation is achieved is via angiotensinogen's Cys18–Cys138 disulfide bond that acts as a redox switch. Molecular dynamics simulations of each redox state of angiotensinogen reveal subtle dynamic...