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Keywords: retinol
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Biochem J (2021) 478 (19): 3597–3611.
Published: 08 October 2021
...Mark K. Adams; Olga V. Belyaeva; Lizhi Wu; Ivis F. Chaple; Katelyn Dunigan-Russell; Kirill M. Popov; Natalia Y. Kedishvili The hetero-oligomeric retinoid oxidoreductase complex (ROC) catalyzes the interconversion of all- trans -retinol and all- trans -retinaldehyde to maintain the steady-state...
Includes: Supplementary data
Biochem J (2011) 440 (3): 335–347.
Published: 28 November 2011
.... In the present study, investigate the activity of the four human AKR1C enzymes with retinol and retinaldehyde. All of the enzymes except AKR1C2 showed retinaldehyde reductase activity with low K m values (~1 μM). The k cat values were also low (0.18–0.6 min −1 ), except for AKR1C3 reduction of 9- cis...
Includes: Supplementary data
Biochem J (2006) 399 (1): 101–109.
Published: 13 September 2006
...Oriol Gallego; Olga V. Belyaeva; Sergio Porté; F. Xavier Ruiz; Anton V. Stetsenko; Elena V. Shabrova; Natalia V. Kostereva; Jaume Farrés; Xavier Parés; Natalia Y. Kedishvili Retinoic acid biosynthesis in vertebrates occurs in two consecutive steps: the oxidation of retinol to retinaldehyde followed...
Includes: Supplementary data
Biochem J (2004) 383 (2): 295–302.
Published: 08 October 2004
...Andrei MOLOTKOV; Norbert B. GHYSELINCK; Pierre CHAMBON; Gregg DUESTER Vitamin A homoeostasis requires the gene encoding cellular retinol-binding protein-1 ( Crbp1 ) which stimulates conversion of retinol into retinyl esters that serve as a storage form of vitamin A. The gene encoding alcohol...
Biochem J (2003) 373 (3): 973–979.
Published: 01 August 2003
... 6 5 2003 6 5 2003 The Biochemical Society, London ©2003 2003 aldo—keto reductase enzyme kinetics retinoic acid retinol tolrestat Abbreviations used: ADH, alcohol dehydrogenase; AKR, aldo–keto reductase; AR, aldose reductase; ARIs, aldose reductase inhibitors; HSI...