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1-4 of 4
Keywords: retrotranslocation
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Articles
Monika Słomińska-Wojewódzka, Anna Pawlik, Iwona Sokołowska, Jakub Antoniewicz, Grzegorz Węgrzyn, Kirsten Sandvig
Journal:
Biochemical Journal
Biochem J (2014) 457 (3): 485–496.
Published: 10 January 2014
... to the cytosol in a similar manner as misfolded ER proteins. This transport is promoted by EDEM1. In the present study we report that EDEM2 is also involved in ricin retrotranslocation out of the ER. However, the role of EDEM1 and EDEM2 in ricin transport to the cytosol seems to differ. EDEM2 promotes ricin...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2011) 436 (2): 371–385.
Published: 13 May 2011
... retrotranslocation ricin A-chain (RTA) Ricin, the most toxic member of the RIPs (ribosome-inactivating proteins), accumulates to high levels in the endosperm of Ricinus communis seeds. Cell trafficking of this toxin has been extensively studied due to the variety of medical applications in which it can...
Includes: Supplementary data
Articles
Journal:
Biochemical Journal
Biochem J (2010) 429 (1): 63–72.
Published: 14 June 2010
... (calreticulin) is arginylated by ATE1 (arginyl-tRNA protein transferase). We also show that a pool of CRT undergoes retrotranslocation from the ER (endoplasmic reticulum) to the cytosol, because in CRT-knockout cells transfected with full-length CRT (that has the signal peptide), cytoplasmic CRT appears...
Articles
Marjolein KIKKERT, Gerco HASSINK, Martine BAREL, Christian HIRSCH, Fimme Jan van der WAL, Emmanuel WIERTZ
Journal:
Biochemical Journal
Biochem J (2001) 358 (2): 369–377.
Published: 24 August 2001
... ubiquitin system is essential for dislocation of MHC class I molecules from the ER to the cytosol. The Biochemical Society, London ©2001 2001 degradation E1 enzyme proteasome retrotranslocation ubiquitin Abbreviations used: HCMV, human cytomegalovirus; HLA-A2, human leucocyte antigen...