... in solution which are often difficult to quantify. In the present manuscript we show that the combination of MS under nondenaturing conditions and AUC-SV (analytical ultracentrifugation sedimentation velocity) unambiguously clarifies a distribution of states and hydrodynamic shapes of assembled oligomers...

... Society 2009 caspase-6 caspase activation Huntington's disease multi-angle light scattering (MALS) pre-steady-state kinetics sedimentation velocity All chemicals used were purchased from Sigma–Aldrich unless stated otherwise. Crystallization solutions were all from Hampton Research...