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Keywords: sigma-1 receptor
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Articles

Sigma-1 receptors: a new pathway for the modulation of store-operated calcium entry

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Juan A. Rosado
Journal: Biochemical Journal
Biochem J (2016) 473 (3): e9–e10.
https://doi.org/10.1042/BJ20151144
Published: 25 January 2016
... the expression and activation of the sigma-1 receptor, a chaperone located in the endoplasmic reticulum–mitochondrion interface that modulates intracellular Ca 2+ homoeostasis and cell survival. This study envisages a pathway through which cocaine modulates endothelial function via regulation of SOCE...
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Articles

Cocaine inhibits store-operated Ca 2+ entry in brain microvascular endothelial cells: critical role for sigma-1 receptors

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G. Cristina Brailoiu, Elena Deliu, Linda M. Console-Bram, Jonathan Soboloff, Mary E. Abood, Ellen M. Unterwald, Eugen Brailoiu
Journal: Biochemical Journal
Biochem J (2016) 473 (1): 1–5.
https://doi.org/10.1042/BJ20150934
Published: 09 December 2015
...G. Cristina Brailoiu; Elena Deliu; Linda M. Console-Bram; Jonathan Soboloff; Mary E. Abood; Ellen M. Unterwald; Eugen Brailoiu Sigma-1 receptor (Sig-1R) is an intracellular chaperone protein with many ligands, located at the endoplasmic reticulum (ER). Binding of cocaine to Sig-1R has previously...
View article titled, Cocaine inhibits store-operated Ca 2+ entry in brain microvascular endothelial cells: critical role for sigma-1 receptors
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