... ]. cytokine epigenetic change interferon Janus kinase (JAK) signal transducer and activator of transcription (STAT) steroid steroid-like signalling The dominant role that has been placed upon STAT (signal transducer and activator of transcription) transcription factors in gene activation...

... extracellular matrix (ECM) mammary gland nitric oxide nuclear factor κB (NF-κB) signal transducer and activator of transcription (STAT) weaning Mammary gland is a highly dynamic and specialized tissue which development takes place postnatally. During pregnancy, there is epithelial cell...

... 7 2009 © The Authors Journal compilation © 2009 Biochemical Society 2009 flagellin gut epithelium inflammation interferon γ myeloid differentiation factor 88 (MyD88) signal transducer and activator of transcription (STAT) The gut is colonized by a large and very diverse...

... in response to IL-6 [ 15 ]. cytokine inflammation interleukin-6 (IL-6) Janus kinase (JAK) prostaglandin (PG) signal transducer and activator of transcription (STAT) signal transduction MCP-1 is induced during inflammation by a number of inflammatory agents, including IL-6. Since PGE 1...

... that the interplay between SUMOylation and Ser 727 phosphorylation is involved in fine-tuning the transcriptional responses during immune responses to bacterial infections, stress stimuli and growth signals. mitogen-activated protein kinase (MAPK) signal transducer and activator of transcription (STAT...

... 7 2007 13 7 2007 © The Authors Journal compilation © 2007 Biochemical Society 2007 interferon α (IFNα) interferon β (IFNβ) interferon α/β receptor internalization Janus kinase (JAK) signal transducer and activator of transcription (STAT) Since IFNAR1 is the low...

... be addressed (email [email protected] ). 26 4 2006 11 7 2006 4 8 2006 4 8 2006 The Biochemical Society, London 2006 iron metabolism iron regulatory protein 1 (IRP1) nitric oxide promoter regulation signal transducer and activator of transcription (STAT) transcription...

..., Tat protein interacts intracellularly with IRF-1, disrupting STAT1–IRF-1 complex formation and preventing basal LMP2 gene expression. antigen processing HIV interferon immunoproteasome signal transducer and activator of transcription (STAT) Tat Protein turnover in the cell...

... 2003 The Biochemical Society, London ©2003 2003 cytokine signalling glycoprotein 130 (gp 130) interleukin-6 (IL-6) Janus kinase (JAK) mitogen-activated protein kinase (MAPK) signal transducer and activator of transcription (STAT) Abbreviations used: α 2 M, α 2 -macroglobulin...

... and the intracellular domain of LICR2, activated signal transducer and activator of transcription (STAT)1, STAT2, STAT3 and STAT5 upon IL-10 stimulation, in a Janus kinase 1-dependent manner. In contrast, none of the IL-10-related cytokines described so far could activate LICR2-transfected cells, suggesting that LICR2...