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Keywords: splice variants
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Articles

Superoxide generation from nNOS splice variants and its potential involvement in redox signal regulation

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Hideshi Ihara, Atsushi Kitamura, Shingo Kasamatsu, Tomoaki Ida, Yuki Kakihana, Hiroyasu Tsutsuki, Tomohiro Sawa, Yasuo Watanabe, Takaaki Akaike
Journal: Biochemical Journal
Biochem J (2017) 474 (7): 1149–1162.
https://doi.org/10.1042/BCJ20160999
Published: 15 March 2017
...Hideshi Ihara; Atsushi Kitamura; Shingo Kasamatsu; Tomoaki Ida; Yuki Kakihana; Hiroyasu Tsutsuki; Tomohiro Sawa; Yasuo Watanabe; Takaaki Akaike We previously demonstrated different spacial expression profiles of the neuronal nitric oxide (NO) synthase (nNOS) splice variants nNOS-µ and nNOS-α...
View article titled, Superoxide generation from nNOS splice variants and its potential involvement in redox signal regulation
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Articles

A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis

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Mhairi C. Towler, Sarah Fogarty, Simon A. Hawley, David A. Pan, David M. A. Martin, Nicolas A. Morrice, Afshan McCarthy, María N. Galardo, Silvina B. Meroni, Selva B. Cigorraga, Alan Ashworth, Kei Sakamoto, D. Grahame Hardie
Journal: Biochemical Journal
Biochem J (2008) 416 (1): 1–14.
https://doi.org/10.1042/BJ20081447
Published: 28 October 2008
... syndrome, and is a gene involved in cell polarity as well as an upstream protein kinase for members of the AMP-activated protein kinase family. We report that mammals express two splice variants caused by alternate usage of 3′-exons. LKB1 L is the previously described form, while LKB1 S is a novel form...
View article titled, A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis
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Includes: Supplementary data
Articles

Differential expression of a C-terminal splice variant of phosphatidylinositol transfer protein β lacking the constitutive-phosphorylated Ser 262 that localizes to the Golgi compartment

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Clive P. Morgan, Victoria Allen-Baume, Marko Radulovic, Michelle Li, Alison Skippen, Shamshad Cockcroft
Journal: Biochemical Journal
Biochem J (2006) 398 (3): 411–421.
https://doi.org/10.1042/BJ20060420
Published: 29 August 2006
... reported that Ser 262 present in the C-terminus of PITPβ is constitutively phosphorylated and determines Golgi localization. We provide evidence for the expression of an sp (splice) variant of PITPβ (PITPβ-sp2) where the C-terminal 15 amino acids of PITPβ-sp1 are replaced by an alternative C-terminus of 16...
View article titled, Differential expression of a C-terminal splice variant of phosphatidylinositol transfer protein β lacking the constitutive-phosphorylated Ser 262 that localizes to the Golgi compartment
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Includes: Supplementary data
Articles

C-terminal domain of rodent intestinal mucin Muc3 is proteolytically cleaved in the endoplasmic reticulum to generate extracellular and membrane components

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Rongquan WANG, Ismat A. KHATRI, Janet F. FORSTNER
Journal: Biochemical Journal
Biochem J (2002) 366 (2): 623–631.
https://doi.org/10.1042/bj20020289
Published: 01 September 2002
... of soluble splice variants; however, experiments with heterologous cells transfected with cDNA encoding the 381-residue C-terminal domain of rodent Muc3 showed that a definitive proteolytic cleavage occurs during processing in the endoplasmic reticulum. The products consisted of a V5-tagged 30kDa...
View article titled, C-terminal domain of rodent intestinal mucin Muc3 is proteolytically cleaved in the endoplasmic reticulum to generate extracellular and membrane components
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