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Keywords: stable isotope
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Articles

Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes

Open Access
Andrew A. Gibb, Pawel K. Lorkiewicz, Yu-Ting Zheng, Xiang Zhang, Aruni Bhatnagar, Steven P. Jones, Bradford G. Hill
Journal: Biochemical Journal
Biochem J (2017) 474 (16): 2785–2801.
https://doi.org/10.1042/BCJ20170474
Published: 07 August 2017
... of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) . cardiac hypertrophy glycolysis heart failure metabolomics mitochondria stable isotope All values are mean ± SEM. All comparisons were made to the relevant control group and performed...
View articletitled, Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes
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Articles

Modification degrees at specific sites on heparan sulphate: an approach to measure chemical modifications on biological molecules with stable isotope labelling

Available to Purchase
Zhengliang L. Wu, Miroslaw Lech
Journal: Biochemical Journal
Biochem J (2005) 389 (2): 383–388.
https://doi.org/10.1042/BJ20041827
Published: 05 July 2005
... sulphation levels, which allows cells to tune their affinities to various extracellular proteins, including growth factors. With stable isotope labelling and HPLC-coupled MS, modification degrees at various O-sulphation sites could be determined. A bovine kidney HS sample was first saturated in vitro with 34...
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Includes: Supplementary data
Articles

Ceramide metabolite, not intact ceramide molecule, may be responsible for cellular toxicity

Available to Purchase
Kou-Yi TSERNG, Ronda L. GRIFFIN
Journal: Biochemical Journal
Biochem J (2004) 380 (3): 715–722.
https://doi.org/10.1042/bj20031733
Published: 15 June 2004
.... Using stable isotope labelling coupled with GC (gas chromatography)-MS and mass isotopomer distribution analysis, we have studied the metabolism of exogenous long-chain ceramides in HL60 cells. Our results do not support the concept of enhanced ceramide transport into cells induced by solvent mixtures...
View articletitled, Ceramide metabolite, not intact ceramide molecule, may be responsible for cellular toxicity
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