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Keywords: stem cells
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Biochem J (2017) 474 (11): 1755–1768.
Published: 10 May 2017
... role of RUNX1. Furthermore, in solid cancers, RUNX1 is overexpressed compared with normal tissue, and RUNX factors have recently been discovered to promote growth of skin, oral, breast and ovarian tumour cells, amongst others. RUNX factors have key roles in stem cell fate regulation during homeostasis...
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