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Keywords: steroidogenesis
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Biochem J (2018) 475 (5): 901–904.
Published: 06 March 2018
...Barbara Costa; Eleonora Da Pozzo; Claudia Martini Two interesting papers by Barren et al. and Owen et al. have been very recently published in Biochemical Journal , reporting the role of translocator protein (TSPO) in steroidogenesis. The involvement of TSPO in the steroid biosynthesis has been...
Biochem J (2018) 475 (1): 75–85.
Published: 02 January 2018
... steroidogenesis has recently been challenged by the development of TSPO knockout (TSPO-KO) mice, as they exhibit normal baseline gonadal testosterone and adrenal corticosteroid production. Here, we demonstrate that despite normal androgen levels in young male TSPO-KO mice, TSPO deficiency alters steroidogenic...
Biochem J (2014) 460 (3): 459–471.
Published: 29 May 2014
... steroidogenesis. Previously, we have found that SF-1 induces the differentiation of mesenchymal stem cells into steroidogenic cells. To elucidate the molecular mechanisms of SF-1-mediated functions, we attempted to identify protein components of the SF-1 nuclear protein complex in differentiated cells. SF-1...
Includes: Supplementary data
Biochem J (2010) 432 (3): 473–486.
Published: 25 November 2010
... and Y-1 cells respectively. Finally, we demonstrated that PGC-1α induces SF-1 gene expression in both αT3-1 and Y-1 cells. Taken together, our findings reveal the potential role of PGC-1α and suggest that it may play important roles in steroidogenesis, gonad development and sex differentiation through...
Includes: Supplementary data
Biochem J (2010) 431 (1): 159–167.
Published: 14 September 2010
... enzyme lend support to the notion that particular GSTs play an important role in steroidogenesis. 1 To whom correspondence should be addressed (email Bengt.Mannervik@biorg.uu.se ). 8 6 2010 29 7 2010 30 7 2010 30 7 2010 © The Authors Journal compilation © 2010...
Includes: Supplementary data
Biochem J (2009) 419 (1): 201–209.
Published: 13 March 2009
... (PIAS) steroidogenesis steroid receptor co-activator-1 (SRC-1) SUMOylation LRH-1 (liver receptor homologue-1; NR5A2), related to the Drosophila Ftz-F1 ( Fushi tarazu factor 1), belongs to the nuclear hormone receptor NR5A subfamily [ 1 ]. LRH-1-null mice die at embryonic day 7.5...
Biochem J (2008) 412 (3): 553–562.
Published: 28 May 2008
...Alireza Roostaee; Élie Barbar; Jean-Guy LeHoux; Pierre Lavigne Steroidogenesis depends on the delivery of cholesterol from the outer to the inner mitochondrial membrane by StAR (steroidogenic acute regulatory protein). However, the mechanism by which StAR binds to cholesterol and its importance in...
Includes: Supplementary data
Biochem J (2000) 350 (3): 785–790.
Published: 08 September 2000
... nuclear receptors steroidogenesis transcription Biochem. J. (2000) 350, 785 790 (Printed in Great Britain) 785 Contribution of steroidogenic factor 1 to the regulation of cholesterol synthesis Cristina MASCARO! , Alicia NADAL, Fausto G. HEGARDT, Pedro F. MARRERO and Diego HARO1 Department of...