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Keywords: striatum
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Cecilie Morland, Anne-Sofie Frøland, Mi Nguyen Pettersen, Jon Storm-Mathisen, Vidar Gundersen, Frode Rise, Bjørnar Hassel
Journal:
Biochemical Journal
Biochem J (2018) 475 (4): 749–758.
Published: 16 February 2018
... be seen from increased neuronal histone H4 acetylation in the striatum and neocortex. Propionate caused an increase in GABA (γ-amino butyric acid) levels in the brain, suggesting inhibition of GABA breakdown. In vitro propionate inhibited GABA transaminase with a K i of ∼1 mmol/l. In isolated nerve...