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Keywords: structural biology
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Articles
Biochem J (2020) 477 (18): 3499–3525.
Published: 24 September 2020
... behalf of the Biochemical Society 2020 cryo-EM origin recognition complex replication origin replicative helicase replisome structural biology Although the double helix structure of DNA is elegantly simple, the molecular machinery that duplicates the DNA is remarkably complex. Seventy...
Articles
Biochem J (2020) 477 (12): 2401–2419.
Published: 26 June 2020
... is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY) . co-operativity Mycobacterium tuberculosis regulation structural biology toxin-antitoxin system transcription...
Includes: Supplementary data
Articles
Biochem J (2020) 477 (7): 1219–1225.
Published: 09 April 2020
... , 14498 – 14510 10.1021/jacs.8b09618 Correspondence: Nikolai N. Sluchanko ( nikolai.sluchanko@mail.ru ) interaction networks multivalency phosphorylation protein complexes protein-protein interactions structural biology Discovered in 1967 [ 1 ], 14-3-3 proteins became one...
Articles
Biochem J (2016) 473 (11): 1593–1604.
Published: 27 May 2016
... suggest that Gremlin-1 does not inhibit BMP-2 by direct 1:1 binding, but possibly has a novel mechanism of sequestering BMP-2 into a larger oligomeric complex. bone morphogenetic protein (BMP) differential screening-aberrative in neuroblastoma (DAN) extracellular antagonism Gremlin structural...
Includes: Supplementary data
Articles
Biochem J (2015) 465 (2): 325–335.
Published: 06 January 2015
... interaction host specificity protein–protein interaction Streptococcus pneumoniae structural biology The complement system is a major component of vertebrate innate immunity and one of the most important frontline defenders against microbial invaders [ 1 , 2 ]. Uncontrolled or inappropriate...
Includes: Supplementary data
Articles
Biochem J (2014) 461 (3): 349–369.
Published: 10 July 2014
... rapid advances in drug discovery approaches and technologies, with three major methods for antimalarial drug development emerging: (i) chemistry-based, (ii) target-based, and (iii) cell-based. Common to all three of these approaches is the unique ability of structural biology to inform and accelerate...
Articles
Biochem J (2012) 441 (2): 591–597.
Published: 21 December 2011
... complex (NTC) spliceosome structural biology zinc finger © The Authors Journal compilation © 2012 Biochemical Society 2012 29 7 2011 27 9 2011 30 9 2011 30 9 2011 The structure of the mRNA splicing complex component Cwc2 amino acids 1–121+133–227 and 1–127 alone have...
Includes: Supplementary data
Articles
Biochem J (2011) 438 (2): 255–263.
Published: 12 August 2011
... N-terminal domain (ATD) structural biology iGluRs (ionotropic glutamate receptors) are ligand-gated ion channels that form transmembrane cation-permeable channels. iGluRs exist as three distinct sub-families according to their agonist specificity and amino acid sequence: AMPARs (α-amino-3...
Includes: Supplementary data
Articles
Biochem J (2010) 425 (3): 475–488.
Published: 15 January 2010
... © The Authors Journal compilation © 2010 Biochemical Society 2010 chaperone-usher protein secretion structural biology type IV secretion virulence factor Gram-negative bacteria have evolved several simple to complex machineries for transport of substrates across their cell membrane in...