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1-3 of 3
Keywords: structural model
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Articles
Alanine scanning mutagenesis of a high-affinity nitrate transporter highlights the requirement for glycine and asparagine residues in the two nitrate signature motifs
Available to PurchaseShiela E. Unkles, Eugenia Karabika, Vicki F. Symington, Jennifer L. Cecile, Duncan A. Rouch, Naureen Akhtar, Brett A. Cromer, James R. Kinghorn
Journal:
Biochemical Journal
Biochem J (2012) 447 (1): 35–42.
Published: 12 September 2012
.... Although perfectly conserved substrate-interacting arginine residues have been described in transmembrane helices 2 and 8, the role of NSs has not been investigated. In the present study, a combination of structural modelling of NrtA (nitrate transporter from Aspergillus nidulans ) with alanine scanning...
Articles
EmbR2, a structural homologue of EmbR, inhibits the Mycobacterium tuberculosis kinase/substrate pair PknH/EmbR
Available to PurchaseVirginie Molle, Robert C. Reynolds, Luke J. Alderwick, Gurdyal S. Besra, Alain J. Cozzone, Klaus Fütterer, Laurent Kremer
Journal:
Biochemical Journal
Biochem J (2008) 410 (2): 309–317.
Published: 12 February 2008
... forkhead-associated domain (FHA domain) Mycobacterium PknH serine/threonine protein kinase structural model Figure 1 Genome location, sequence similarity and proposed backbone structure of EmbR2 ( A ) Organization of the region of insertion containing the embR2 locus in M. tuberculosis...
Articles
Rat glutathione S-transferase M4-4: an isoenzyme with unique structural features including a redox-reactive cysteine-115 residue that forms mixed disulphides with glutathione
Available to PurchaseHailing CHENG, Tatyana TCHAIKOVSKAYA, Yen-Sheng L. TU, Jason CHAPMAN, Biao QIAN, Wei-Mei CHING, Ming TIEN, Jonathan D. ROWE, Yury V. PATSKOVSKY, Irving LISTOWSKY, Chen-Pei D. TU
Journal:
Biochemical Journal
Biochem J (2001) 356 (2): 403–414.
Published: 24 May 2001
... with redox-active Cys-115 residues could have specialized physiological functions in re- sponse to oxidative stress. Key words: glutathiolation, mass spectrometry, oxidative stress, structural model, synthetic gene. sequence of the putative rGSTM4 subunit (originally designated as GST-Y b% , GenBank...