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Keywords: substrate
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Biochem J (2021) 478 (12): 2233–2245.
Published: 18 June 2021
...Izabela Maluch; Justyna Grzymska; Scott J. Snipas; Guy S. Salvesen; Marcin Drag Caspases are a family of enzymes that play roles in cell death and inflammation. It has been suggested that in the execution phase of the apoptotic pathway, caspase-3, -6 and -7 are involved. The substrate specificities...
Includes: Supplementary data
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Biochem J (2011) 433 (2): 277–284.
Published: 22 December 2010
...Sheng Chen; Hoi Ying Wan BoNTs (botulinum neurotoxins) are both deadly neurotoxins and natural toxins that are widely used in protein therapies to treat numerous neurological disorders of dystonia and spinal spasticity. Understanding the mechanism of action and substrate specificity of BoNTs...
Includes: Supplementary data
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Biochem J (2009) 418 (1): 93–101.
Published: 28 January 2009
... substrates, however, remain unknown. In a yeast two-hybrid screen of a human heart cDNA library with a dominant-negative Mst1 (K59R) mutant used as bait, cTn [cardiac Tn (troponin)] I was identified as an Mst1-interacting protein. The interaction of cTnI with Mst1 was confirmed by co-immunoprecipitation...
Includes: Supplementary data
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