... ]. ATP-binding cassette transporter A1 (ABCA1) murine lung epithelium phosphatidylcholine Pseudomonas aeruginosa secretory phospholipase A 2 IB (sPLA 2 IB) surfactant Six-week-old male C57BL/6J mice weighing 20–25 g were deeply anaesthetized intraperitoneally with ketamine (60–100 mg/kg...

..., and so on. Surfactant secretagogues such as ATP and ionomycin stimulate the release and transmembrane influx of Ca 2+ , both of which increase [Ca 2+ ] i . The addition of surfactant protein A (SP-A) or depleting cellular Ca 2+ inhibited both surfactant secretion and Ca 2+ transients. Current results...