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Keywords: syntaxin
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Articles
Biochem J (2021) 478 (7): 1471–1484.
Published: 16 April 2021
... of the C-terminal tail region of tau and identified syntaxin 8 (STX8) as a mediator of tau release from cells. Similarly, we showed the syntaxin 6 (STX6), part of the same SNARE family as STX8 also facilitated tau release. STX6 was previously genetically linked to progressive supranuclear palsy (PSP...
Includes: Supplementary data
Articles
Biochem J (2009) 418 (1): e1–e3.
Published: 28 January 2009
...Mary Munson; Nia J. Bryant Intracellular membrane fusion steps in eukaryotes require the syntaxin family of SNARE (soluble N -ethylmaleimide-sensitive fusion protein-attachment protein receptor) proteins. Syntaxins are regulated at several levels through interactions with regulatory proteins...
Articles
Biochem J (2008) 410 (1): 93–100.
Published: 29 January 2008
... classified into Q-SNARE and R-SNARE based on the structural property of their motifs. Assembly of four SNARE motifs (Qa, b, c and R) is supposed to trigger membrane fusion. We have previously shown that ER (endoplasmic reticulum)-localized syntaxin 18 (Qa) forms a complex with BNIP1 (Qb), p31/Use1 (Qc...
Articles
Biochem J (2005) 392 (2): 283–289.
Published: 22 November 2005
... specifically with syntaxin 1, a 35 kDa membrane protein, to mediate the fusion process. Here, we investigated whether other known syntaxin isoforms found at the plasma membrane can serve as binding partners for SNAP-25 in vivo . In our analysis, we employed rat phaeochromocytoma PC12 cells that are often used...
Includes: Supplementary data
Articles
Biochem J (2005) 388 (1): 75–79.
Published: 10 May 2005
...Colin RICKMAN; Kuang HU; Joe CARROLL; Bazbek DAVLETOV Three evolutionarily conserved proteins known as SNAREs (soluble N -ethylmaleimide-sensitive fusion protein attachment protein receptors) mediate exocytosis from single cell eukaryotes to neurons. Among neuronal SNAREs, syntaxin and SNAP-25...
Includes: Supplementary data
Articles
Biochem J (2005) 387 (1): 195–202.
Published: 22 March 2005
... dominant membrane-repolarizing Kv channels (voltage-gated K + channels), such as Kv2.1, in pancreatic β-cells. In a recent report, we demonstrated that WT (wild-type) Syn-1A (syntaxin-1A) inhibits Kv2.1 channel trafficking and gating through binding to the cytoplasmic C-terminus of Kv2.1. During β-cell...
Articles
Biochem J (2003) 375 (2): 433–440.
Published: 15 October 2003
...Penelope BUXTON; Xiang-Ming ZHANG; Bong WALSH; Absorn SRIRATANA; Irina SCHENBERG; Elizabeth MANICKAM; Tony ROWE Members of the SNARE (soluble N -ethylmaleimide-sensitive fusion protein attachment protein receptor) superfamily [syntaxins, VAMPs (vesicle-associated membrane proteins) and SNAP25...
Articles
Biochem J (2003) 374 (1): 207–217.
Published: 15 August 2003
... regulate specific syntaxin t-SNAREs. In resting platelets, these SM proteins associate with granules and open canalicular system membranes predominantly but not with the plasma membrane. Munc18a binds to syntaxin 2 alone and does not associate with other members of the core SNARE complex. Munc18b...
Articles
Biochem J (2001) 357 (3): 625–634.
Published: 25 July 2001
... complex that includes the plasma membrane target soluble N -ethylmaleimide-sensitive fusion protein (NSF) attachment protein (SNAP) receptors (t-SNAREs), syntaxin 1A and synaptosome-associated protein of 25kDa (SNAP-25), and the vesicle SNARE (v-SNARE), vesicle-associated membrane protein (VAMP). Whereas...
Articles
Biochem J (1999) 338 (3): 709–715.
Published: 08 March 1999
... NSF attachment protein]. The SNARE proteins syntaxin 4 and vesicle-associated membrane protein (VAMP) 2/3 also participate in the insulin-stimulated translocation of GLUT4 from intracellular vesicles to the plasma membrane in adipose cells. We now report the molecular cloning and characterization of...