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Keywords: tertiary structure model
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Articles
Prediction of hammerhead ribozyme intracellular activity with the catalytic core fingerprint
Available to Purchase
Journal:
Biochemical Journal
Biochem J (2013) 451 (3): 439–451.
Published: 12 April 2013
.... In the present paper we describe a new extended hammerhead ribozyme HH-2 with a tertiary stabilizing motif constructed on the basis of the tetraloop receptor sequence. This ribozyme is very active in living cells, but shows low activity in vitro . To understand it, we analysed tertiary structure models...
Includes: Supplementary data