... half-cell reactions (4a and 5a), and calculated via eqns (4b and 5b), respectively: 4a glutaredoxins thiol–disulfide exchange reduction potential Reversible thiol–disulfide exchange reactions act as versatile redox switches for protein thiols and play important roles in a wide...

... thiol-disulfide exchange reactions and indicate that there is no kinetic barrier to the exchange of disulfides between several PDI proteins. Such promiscuous disulfide exchange negates the necessity for each enzyme to be oxidized by Ero1 (ER oxidoreductin 1) or reduced by a reductive system. The lack...